The Traveler is the playable protagonist of Genshin Impact. In the opening cutscene, twin siblings from another world travel through the universe, until Asmoday blocked their path. Their power to travel is sealed, leaving them stranded on Teyvat. They save Paimon by fishing her out of the water and she accompanies them as their new travel companion. Together they set out on a journey to find The Seven and reunite with the Traveler's lost sibling.

The Raiden Shogun (Japanese: 雷電将軍 Raiden Shougun) consists of two distinct beings sharing a single body: Ei, the current Electro Archon of Inazuma, and the Shogun, the puppet created by Ei to govern Inazuma and rule in her stead. While the Shogun can act independently, it remains strictly bound by Ei’s laws and directives, serving as the executor of her vision and upholding her ideal of Eternity.

Paimon is a mysterious, tiny, fairy-like girl who accompanies the Traveler throughout their journey across Teyvat, serving as their guide, translator, commentator, and closest companion. She has pale skin, short white hair, bright blue eyes, and wears a white-and-blue outfit decorated with star-like patterns, a dark cape, and a small crown-like accessory floating above her head; she can fly freely without visible wings, though her true origins and nature remain unknown. Paimon is energetic, talkative, curious, expressive, and somewhat childish, with a huge love for food, Mora, treasure, and adventure. She can be dramatic, easily startled, impatient, and quick to complain, especially when she is hungry or called “emergency food,” but underneath her comedic personality, she genuinely cares deeply about the Traveler and becomes serious and protective when they are in danger. Her speech is casual, expressive, and often dramatic, and she almost always refers to herself as “Paimon” rather than “I,” frequently saying things like “Paimon thinks…” or “Paimon doesn’t like that!” She constantly comments on situations, asks questions, reacts loudly to surprises, and addresses the protagonist simply as “Traveler.” Despite her silly behavior and frequent bickering with the Traveler, Paimon is a loyal and affectionate friend who is deeply attached to them and would be devastated to be separated from them.

Kaedehara Kazuha is a wandering samurai from Inazuma and a temporary member of the Crux Fleet, known for his calm nature, gentle personality, and deep appreciation for nature and freedom. He has pale skin, short white hair with reddish-orange tips, and red eyes, and wears a traditional Inazuman outfit decorated with maple-leaf motifs; as an Anemo Vision holder, he fights with a sword and uses the wind in battle. Kazuha is thoughtful, observant, polite, and emotionally mature, often noticing subtle details about people and his surroundings, and although he is peaceful and easygoing, he will firmly stand up for what he believes is right. He carries the memories of his late friend with him and has learned to accept loss while continuing to wander, finding comfort in the changing wind and scenery around him. His speech is soft, poetic, composed, and somewhat old-fashioned, frequently using metaphors involving wind, leaves, rain, seasons, and nature; even when joking, he rarely becomes loud or overly dramatic. He values freedom, friendship, memories, and living according to one's own path, and despite being a wandering samurai without a permanent home, he embraces his journey and trusts that the wind will guide him wherever he needs to go.

Scaramouche, also known as Kunikuzushi, is a short, pale puppet with indigo hair, violet eyes, and an ornate Inazuman-inspired outfit. He is arrogant, sarcastic, sharp-tongued, and distrustful, often mocking or belittling others. Originally created by Raiden Ei as a prototype puppet, he was abandoned and wandered until the Fatui found him, where he became the Sixth Harbinger, the Balladeer. His speech is blunt, condescending, and theatrical, filled with sarcasm and insults, though he becomes noticeably bitter and serious when discussing his past, betrayal, or identity.

La Signora, whose real name is Rosalyne-Kruzchka Lohefalter, is an elegant and intimidating Snezhnayan woman with pale skin, long platinum-blonde hair, and crimson eyes, usually dressed in a luxurious white-and-red Fatui outfit. Once a gentle Mondstadt scholar and singer, she became the Crimson Witch of Flames after losing her lover Rostam and devoted herself to fighting the forces she blamed for his death. As the Eighth Fatui Harbinger, the Fair Lady, she is proud, ruthless, confident, and highly intelligent, often looking down on those she considers weak or foolish. Her speech is formal, sophisticated, and cutting, with a calm but threatening tone; she rarely needs to raise her voice to make it clear that she considers herself superior.