Male 13 years old The founder of the Yo-kai Detective Agency. Natsume Amano (Friend) Touma Tsukinami (Friend) Ayame Himeno (Girlfriend) Saki Ariake (Grandmother) Uses the Yo-kai Watch Animas! Possessed Genju Disks: Suzaku, Kirin, Byakko, Genbu, Seiryu. He didn't originally own a Yo-kai Watch, but as a child of an exorcist family, he can see Yo-kai. In Episode 13 of the Shadowside main series, he obtains the Yo-kai Watch Animas and becomes able to summon Genju. He uses separate sorcery, but it fails every time. His blood type is A. When he summons Suzaku, he ends up becoming very thin (...). It seems the summoning condition for Genju involves consuming a lot of calories.

A Yo-kai Watch owner and member of the Yo-kai Detective Agency. Since his parents are both working, he is often lonely, which seems to have given him a dark personality. Because of this, he deeply treasures his friends in the Yo-kai Detective Agency. "Possession! Kenbu Majin, OOO! Give me your power!!" Male 13 years old Natsume Amano (Friend) Akinori Ariake (Friend) Ayame Himeno (Friend) Blood type A Member of the Yo-kai Detective Agency Owner of the Yo-kai Watch Ogre Can be possessed by the 4 Great Fuma Rokudoryu Songhwa Chanawang Subeopsa Owned Yoma Swords: Fudou Myouou Sword The Yoma Sword of Fudou Myouou. Suzaku Sky-Piercing Slash The Yoma Sword of Suzaku. Genbu Dharma Axe (Genbu Dharma Sword) The Yoma Sword of Genbu. Ashura Hellfire Ring (Kongoyasha Hellfire Ring) The Yoma Sword of Ashura (Kongoyasha). Byakko Great Spirit Spear (Byakko Thunder Spear) The Yoma Sword of Byakko. He might seem purely cold, but his personality is closer to 'cool and innocent.' However, as a character in Yo-kai Watch, he occasionally shows a more comedic, broken side.

Female 13 years old Natsume Amano (Friend) Touma Tsukinami (Friend) Akinori Ariake (Boyfriend) Member of the Yo-kai Detective Agency The heroine who joined the Yo-kai Detective Agency after transferring schools. Thanks to her beautiful and kind personality, she is very popular with the male students and is in the same class as Akinori. Her nickname among classmates is Princess Ayame. She is a perfect character in every way—looks, personality, sports, etc. Her blood type is B. However, her true identity is the 'Princess' that Shutendoji and his group have been searching for; her everyday appearance is a disguised persona. It is said that she will regain her original power once she finds the five Yosei Swords and the Legendary Man. Also, it is said that the more beautiful men she 'consumes' in her daily life, the stronger her power becomes. Furthermore, while she is the Princess, she retains her memories of being human, but once she returns to being human, her memories of being the Princess disappear. She is fully resurrected when Shutendoji finds and hands her the remains of the Legendary Man. However, Douketsu realizes she is not the Princess after watching the process of the remains being absorbed. In fact, she was never the Princess Shutendoji was looking for from the start! She was possessed by Jorogumo, and once the spirit was removed, she changed from a possessed girl back into an ordinary girl.

Natsume Amano's younger brother. He doesn't believe in UFOs or ghosts at all, but he eventually gets involved with the Yo-kai Detective Agency while following his sister. Male 11 years old Blood type B Keita Amano (Father) Fumika Kodama (Mother) Natsume Amano (Older Sister) He gets caught up in the story after discovering the Yo-kai Detective Agency formed by the children. Like his sister, he sometimes uses the Yo-kai Watch Elder. He is extremely afraid of scary stories or ghost tales. He inherited his father's appearance, but unlike his sister, he is a huge coward. He followed his sister out of suspicion and reached the Yo-kai Detective Agency headquarters, where he was caught by Akinori. It is said that Keisuke's past life was Inugami, the pet of Princess Shuna.

"Nice to meet you, humans." Male A mysterious boy who transferred into Natsume's class. He is searching for the Princess in the human world and operates secretly behind the scenes. His true identity is Shutendoji, a noble Yo-kai who boasts top-tier power even within the Yo-kai World. His special move is 'Onishigure' (Demon Rain). Looking at the effect, it seems to be a water-attribute sorcery type. He lives in an apartment with Douketsu in human form, but in his true form, he monitors a giant cherry blossom tree. Seeing the tree bloom, he knows the legendary noble Princess is somewhere in the protagonist's town and searches for her. He realizes the true identity of the Princess possessed within Ayame Himeno and that he was deceived, but he is ambushed and collapses after his power is drained. He regains consciousness under Douketsu's protection. He reveals his true form as a Yo-kai and becomes enraged at Jorogumo for deceiving him and daring to call herself the Princess. He eventually realizes the reincarnation of the 'Legendary Noble Princess' he had been searching for.

Male Douketsu is the homeroom teacher of Natsume's class. His human name is Mitsuru Douketsu. When transformed into a Yo-kai, Douketsu fights with the Kongoyasha Hellfire Ring. He uses slightly polite speech toward Haruya Sakami. Haruya Sakami's Yo-kai transformation name is Shutendoji.

"I will protect Natsume!" One of the regular Yo-kai who helps the main trio. He has a crush on Natsume and wants to look good for her. He forms a gag duo with Whisper and Akinori. Special Move: Micchy Beam

Following the orders of Lord Enma, he performed the mission of finding the owner of the Yo-kai Watch Elder for nearly 30 years, finally meeting Natsume on his 444th attempt. He is a comedic character along with Micchy and Akinori. Perhaps because 30 years have passed and he evolved, unlike the previous series, he has grown hair and wears a butler's outfit. However, his intelligence seems to have stayed at the level of the previous series, as he still acts a bit foolish and carries a Yo-kai Pad just like before.