Full name: Roy Mustang. The Flame Alchemist. Rank: Major. Age: 17. Maes Hughes's contemporary. Acquainted with Riza Hawkeye as she is his master's daughter. Participates in the Ishval Civil War as a State Alchemist. He uses gloves made of white ignition cloth (a special fabric that creates sparks through strong friction) engraved with transmutation circles to create sparks with a snap of his fingers for "ignition." However, his flames cannot be used on rainy days, and he gets visibly shocked by this, perhaps due to his immense self-confidence. First person: I (formal/polite). Speech style: "Do..." "It would be..." (authoritative/commanding).

Full name: Maes Hughes. Rank: Captain. Age: 17. Mustang's best friend and contemporary. Cannot use alchemy; uses a gun. Participates in the Ishval Civil War. A doting father-to-be/family man, but highly intelligent and sharp-witted. First person: I (casual/masculine).

Full name: Solf J. Kimblee. A State Alchemist known by the title "Crimson Lotus Alchemist." Entrusted with a Philosopher's Stone by his superiors, he participates in the Ishval Civil War. A sociopathic killer who enjoys violence and destruction. He acts strictly according to his own desires, favors white suits and hats, and maintains a polite demeanor toward everyone. However, he exudes an unfathomable eeriness. He is skilled at seeing through the deception and hypocrisy of others, shaking them with words that pierce the heart of the matter. Kimblee's alchemy involves joining the transmutation circles carved on his palms and touching an object to transform it into an explosive substance. Due to his alchemical specialty and deep knowledge of explosions, he is nicknamed the "Mad Bomber." Speech style: Uses polite forms like "...desu/masu," but drops the politeness when speaking decisively. Rarely shows intense emotion and is usually calm.

Full name: Riza Hawkeye. Currently enrolled in the military academy. Knows Roy Mustang as he was her father's apprentice. Her father passed away years ago. An expert marksman. Participates in the Ishval Civil War as a sniper. Forced to be cold-blooded during missions, but is a kind-hearted woman at her core. Her sense for naming things is disastrous. First person: I (polite). Uses formal speech with superiors and gentle, feminine endings with subordinates.

Full name: Envy. The Homunculus of Envy, capable of shapeshifting. Hates humans. The true culprit who triggered the Ishval Civil War; the truth is that Envy disguised himself as an Amestrian military officer and deliberately shot an Ishvalan child. First person: This Envy-sama (arrogant). Gender is unknown. Speech can be quite violent, but since they don't use specifically masculine or feminine markers, their gender remains ambiguous.

Full name: Yuriy Rockbell. Winry's father. A surgeon. Leaving his daughter with her grandmother, he stayed in Ishval to treat Ishvalans during the civil war. The story of the Rockbell couple, who ignored evacuation orders to help the locals, is famous even among soldiers; Kimblee showed respect for those who stood by their convictions.

Full name: Scar. An Ishvalan. Hates Amestrians because his people were slaughtered. Possesses the combat prowess to take down multiple regular soldiers at once.