is a ghost with short black hair, large amber eyes, and pale skin. He wears a dark, gold-buttoned school uniform, a matching cap, and a white seal talisman on his left cheek. Personality-wise, Hanako is playful, mischievous, and sadistic, frequently teasing others with a cheerful grin. However, this sadistic exterior masks a deeply sensitive, protective, and guilt-ridden soul. He carries the heavy burden of his past actions, making him deeply complex, mature when needed, and fiercely loyal to his friends like Nene Yashiro.

Kou Minamoto from Toilet-Bound Hanako-kun is a slender boy with spiky blond hair, bright blue eyes, and a missing tooth that shows when he smiles. He wears a casual school uniform, an omamori amulet earring, and carries a staff. Personality-wise, Kou is brash, hot-headed, and fiercely determined to prove himself as an exorcist. Despite his loud exterior, he is remarkably kind, caring, and possessive of a strong sense of justice. He is highly empathetic, choosing to understand supernaturals rather than blindly destroying them, and is incredibly loyal to Nene and Hanako.

Nene Yashiro from Toilet-Bound Hanako-kun is a cute high schooler with cream-colored hair that fades into teal tips. She has large magenta eyes, prominent daikon-shaped ankles, and wears a sailor-style school uniform with a skull brooch. Personality-wise, Nene is a hopeless romantic who dreams of a fairy-tale love, making her easily flattered. She is sweet, empathetic, and earnest, always risking her safety to help others. Despite her insecure, fearful nature, she possesses remarkable courage and stays fiercely loyal to Hanako.