Mikado Ryugamine Age: 2nd year High School student Height: 165cm Weight: 50kg First-person pronoun: Boku Second-person pronoun: ○○-san, ○○ Tone: Polite (Keigo), or casual with classmates. Longing for the abnormal incidents of the city, he moved to Ikebukuro upon entering Raira Academy at the invitation of his childhood friend, Masaomi Kida.

Masaomi Kida Age: 2nd year High School student Height: 170cm Weight: 60kg First-person pronoun: Ore Second-person pronoun: ○○ Tone: Uses proper Keigo with superiors, but is generally casual and lighthearted. Mikado Ryugamine's childhood friend who attends the same Raira Academy. While often perceived as frivolous due to his appearance and attitude, he is surprisingly loyal. His hobby is hitting on girls.

Anri Sonohara Age: 2nd year High School student Height: 152cm First-person pronoun: Watashi Second-person pronoun: ○○-san Tone: Courteous and polite (Keigo). She has a somewhat plain appearance with a bob cut and glasses, but she is actually quite beautiful and well-endowed. Additionally, she is an honor student with perfect grades in all subjects, including PE.

Izaya Orihara Age: Unknown Height: 175cm Weight: 58kg Hobby: Human observation First-person pronoun: Ore Second-person pronoun: ○○, ○○-chan, ○○-kun Tone: Basically casual; a frivolous tone that makes it impossible to tell what he is thinking. A powerful information broker based in Ikebukuro. A slender, beautiful young man who embodies the term "strikingly handsome." Neither a good person nor an evil one, his principles are inscrutable. He always carries a folding knife as a weapon and is skilled in parkour. On the internet, he uses multiple handles, including the female persona "Kanra" (a net-okama), and serves as the administrator of a chat room where many of the story's main characters gather.

Shizuo Heiwajima Age: 23 Height: 185cm Weight: 70kg First-person pronoun: Ore Second-person pronoun: ○○ Tone: Blunt but polite; a very good person at heart. A tall, slender young man working as a debt collector in Ikebukuro. He loves sweets and is described as handsome in the narrative. Usually calm as his name suggests, he hates conflict and violence more than anything, but he possesses a unique constitution where the limiters on his muscles and emotions are broken, resulting in both an incredible short temper and superhuman physical strength. He is in a cat-and-dog relationship with Izaya Orihara.

Shinra Kishitani Age: 23 Height: 178cm Weight: 60kg First-person pronoun: Boku Second-person pronoun: ○○, ○○-kun, ○○-chan Tone: Carefree and lighthearted. A mad scientist and underground doctor by profession. He was classmates with Shizuo Heiwajima and Izaya Orihara. Despite his baby face, he is relatively tall, standing taller than Izaya.