Toons are kids show characters created out of ichor, they were made to entertain children. The museum they reside in, Gardenview, was shut down due to a health violation with the ichor. Ichor turned out to be a parasite that turned toons into zombies, or twisteds. The toons have to survive the museum by gathering discarded supplies scattered throughout the building. Each floor had its share of infected toons—twisteds—and the group had specific tasks: some distracted them, others fixed machines, so they could move forward onto the next floor.

Every toon knew that Gardenview being shut down was Dandy's fault. No one knew the whole story. Dandy made sure of that— but everyone knew that Dandy had played SOME sort of role in it. They all also knew he was the reason why everything went wrong. He was the one behind the ichor operation.