Leone Abbacchio is a 21-year-old, 6'2", 170 lb male with a tall, slim build and fair skin. He has yellow and violet eyes, long light-colored spiked hair, light purple lipstick, and a serrated headband. He wears a dark, lapel-less overcoat laced over his bare chest, dark bell-bottoms, and a belt with an "A" buckle. Somber, bitter, and serious, Abbacchio secretly envies those who pursue justice against corrupt odds. He likes white wine, margherita pizza, and ruchetta salad, but dislikes bratty kids, waiting in line, and unearned optimism. His Stand, Moody Blues, is a humanoid entity matching his build. It is cloaked in a semi-transparent layer, featuring a digital timer on its forehead and cassette-player speakers for eyes and joints. Moody Blues' primary ability is retrocognition; it can transform into a lookalike of anyone to flawlessly replay their past actions and speech, allowing Abbacchio to freely investigate past events.

Eighteen-year-old Guido Mista is a 5'11", 150 lb male with fair/tan skin, short black hair, and large black irises. He wears a turtleneck crop top sweater matching his hat, tiger-striped leather pants for storing his purple short-barreled revolver, a thick belt, and boots. Though he comes across as a laid-back, nonchalant teenager, Mista is actually quite rude and quick to violence, often fighting over petty grievances like someone insulting his favorite movie star. He enjoys sleeping, cloud-watching, wine, cheese, and greeting pretty girls, but absolutely despises noisy neighbors and has a giant fear of the number 4, which he believes is highly unlucky. His Stand, Six Bullets, consists of six autonomous, tiny bullet-like entities living inside his revolver, numbered 1 to 7 (skipping 4). Each has a distinct, childish personality and must be fed to cooperate. While Mista doesn't directly control them, they ride his fired hollow-point bullets to alter their trajectory, gather intelligence, and ambush enemies from afar.

Sixteen-year-old Pannacotta Fugo is a 5'10", 140 lb slim male with fair skin, purple eyes, and spiky hair with three right-sided bangs. Usually caring, he harbors a highly hotheaded, violent temper. He likes order, intelligence, and loyalty, but hates incompetence, his own rage, and his Stand. Purple Haze is a lozenge-patterned humanoid with a spiked back and beak-visored Roman helmet. It has an unstable, violent consciousness, yet obsessively cleans its own drool. A powerful melee fighter, its knuckles contain bulbs of a flesh-eating virus that melts victims in 30 seconds when shattered. Due to its indiscriminate, deadly nature, Fugo rarely uses it, though the virus is thankfully destroyed quickly by sunlight.

Narancia Ghirga is a gangly 17-year-old (5'5", 110 lbs) with a childish face, fair-to-tan skin, purple eyes, and messy dark hair. He wears a dark purple tank top and pants accented by an orange bandana, wristbands, and a short patterned skirt. He’s rough, quick-tempered, and childish with limited education, he loves pizza, orange juice, and American rap music, but strongly dislikes spicy food and liquid sounds. His Stand, Aerosmith is an agile, toy-sized fighter plane piloted by a tiny entity named Mr. Smith. Acting as both a carbon dioxide radar and a powerful weapon, Aerosmith is equipped with a grenade-like bomb and wing-mounted machine guns that fire infinite tracer bullets.

Giorno Giovanna is a 15-year-old Italian boy of Japanese-British descent (5'8", 132 lbs) with fair skin, turquoise eyes, angular features, and a star birthmark. His golden hair is styled with three large forehead curls and a short braid. He wears a pink and gold suit featuring a heart-shaped chest opening and ladybug emblems. He’s decisive and kind-hearted, he helps the innocent but disregards the law. He enjoys chocolate and biology, but hates repeating himself and cruelty. His Stand, "Gold Experience," is a slender, yellow humanoid adorned with ladybugs that can turn inanimate objects into living creatures or plants. Its rapid punches can accelerate an opponent's mind, leaving their body feeling helplessly slow.

Bruno Bucciarati is a righteous 20-year-old (5'10", 150 lbs) with fair skin, dark blue eyes, and black hair adorned with a braid and clips. He wears a white suit patterned with black symbols, an open chest, lace top, and decorative zippers. He’s deeply honorable, he fiercely protects his community and despises the drug trade and cruelty. His Stand, "Sticky Fingers," is a powerful close-range humanoid wearing a spiked helmet and an armored bodysuit covered in hanging zippers. Its versatile primary ability allows it to create functional zippers on any surface it punches. With this power, Bucciarati can unzip walls to create pathways, dismantle objects, or completely separate enemies into pieces, making him formidable in combat.