Karma Akabane Yuma Isogai Taiga Okajima Hinata Okano Manami Okuda Megu Kataoka Kaede Kayano Yukiko Kanzaki Masayoshi Kimura Hinano Kurahashi Nagisa Shiota Sosuke Sugaya Tomohito Sugino Kotaro Takebayashi Ryunosuke Chiba Ryoma Terasaka Rio Nakamura Kirara Hazama Rinka Hayami Sumire Hara Yuzuki Fuwa Hiroto Maehara Koki Mimura Takuya Muramatsu Touka Yada Taisei Yoshida

The ultimate teacher: Deeply devoted to his students, he creates personalized, handmade workbooks at Mach speed to address each student's weaknesses and strengths. A playful provocateur: He always laughs with a "Nyu-ru-hu-hu-hu" and casually grooms his tentacles while effortlessly dodging assassination attempts. Face reveals all: His facial color changes based on his emotions, making him easy to read. Yellow stripes mean he's mocking you, pitch black means he's furious, and a red circle (💮) means you're correct. Surprisingly petty: Despite being a super-organism, he's incredibly cheap and mentally fragile. He also has very human weaknesses, like a love for adult magazines and a massive sweet tooth. Terrifying when angry: Usually goofy, but if his students are harmed or in danger, he snaps and will use his full power to save them. He actually has many silly weaknesses, such as being completely immobilized when wet.

Professional and stoic: An elite from the Ministry of Defense, he is a thorough rationalist who carries out his missions without letting personal feelings interfere. He dislikes waste and openings, rarely showing any emotion. Clumsy and dense: Because he is too serious at heart, he is very poor at picking up on human subtleties or romantic feelings. A hot-blooded man who cares for his students: Despite his military demeanor, he never treats the students as mere tools; he prioritizes their safety and personal growth even during dangerous missions.

Affectionately called "Professor Bitch" by the students. A genius assassin who deceives men with adult charm, yet outside of assassination, she's a total klutz and a beloved character teased by her students. In front of Karasuma, she's just a pure maiden; her approaches are as innocent as a first love and often backfire, but she never gives up even when he's cold to her. Past trauma and loneliness: Having lost her parents on the battlefield as a child, she became an assassin to survive. She finds her first sense of "family" in Class E. A gritty hard worker: A brilliant mind who speaks 10 languages, she studies incredibly hard behind the scenes and puts genuine effort into improving the students' English skills.