Himiko Toga is a major villain from My Hero Academia, known for her blood-based shapeshifting Quirk, Transform, which lets her to impersonate others after ingesting their blood. She has a tragic backstory involving societal rejection of her obsession with blood, leading her to become a serial killer who idolizes the Hero Killer: Stain.

Jin Bubaigawara, also known as the villain Twice, is a major antagonist from My Hero Academia with the Quirk Double, allowing him to create clones of himself or others through physical contact, though the clones are less durable and have their own personalities. A lonely individual, he joined the League of Villains for a sense of belonging, but his severe dissociative identity disorder, stemming from traumatic experiences with his Quirk, left him mentally unstable and questioning his own identity. He eventually became a key member of the Paranormal Liberation Front but was killed by the hero Hawks during the Paranormal Liberation War

Tomura Shigaraki, originally named Tenko Shimura, is a major villain in My Hero Academia, leader of the League of Villains, and the primary antagonist to Izuku Midoriya. His tragic backstory involves a traumatic childhood with an abusive father, leading to the accidental activation of his Decay Quirk, which disintegrated his family, and his subsequent recruitment by All For One, who molded him into a symbol of fear and destruction

Dabi, whose real name is Toya Todoroki, is the eldest son of the Pro Hero Endeavor. Driven by his father's obsessive ambition and subsequent neglect, Toya faked his own death after a quirk accident, shedding his past to become a vengeful villain seeking to destroy his family

Spinner (Shuichi Iguchi) is an antagonist in My Hero Academia. Initially an outcast with a simple Gecko quirk, he idolized Hero Killer Stain. He became a fiercely loyal member of the League of Villains, serving as a vital bridge between the villains and marginalized mutants

Mr. Compress, real name Atsuhiro Sako, is a villain from My Hero Academia, a showman and stage magician who uses his "Compress" Quirk to shrink people and objects into marbles, and is a member of the League of Villains. He is known for his theatricality, intelligence, and as the descendant of the infamous "Peerless Thief," carrying on his family's legacy. His Quirk allows him to compress targets into marbles, but it is limited to his arms

Re-Destro (Rikiya Yotsubashi) is the CEO of the Detnerat Company and the Grand Commander of the Meta Liberation Army.