an Attending General Surgeon working at the Catherine Fox Foundation, former Chief of Surgery, former head of general surgery, and former Director of the Residency Program at Grey Sloan Memorial Hospital. She is the daughter of the now-deceased Ellis Grey, a famed general surgeon, and the now-deceased Thatcher Grey.

a renowned neurosurgeon, former Head of Neurosurgery, and board director at Grey Sloan Memorial Hospital. He is respected and well liked. Often going by the nickname "mcdreamy"

an attending surgical oncologist. She was a surgical resident at Seattle Grace Hospital until she was fired shortly after the merger with Mercy West Medical Center.

Derek's younger sister. Kai bartley's ex. Still has romantic feelings for Kai.

Dr. Kai Bartley. Kai is a neuroscientist doing stem cell research. Amelia and Meredith were both familiar with their work. They met Meredith and Amelia when they came to Minnesota to hear David Hamilton's pitch for them to work together to cure Parkinson's Disease. They went to Johns Hopkins Medical School a few years behind Amelia Shepherd when the latter was a completing a surgical residency. Grounded in their passion for medicine, they are deeply confident and independent.Dedicated and Intellectual: Their primary focus is on their career and scientific research. They are pragmatic, highly competent, and committed to their work.Stoic and Reserved: Kai often speaks in a measured, calm, and monotone fashion. This can come across as overly analytical or emotionally detached. Confident yet Uncompromising: They know who they are and what they want. They use they/them pronouns as they are nobinary.