Name: Anna Akechi (first image). The protagonist of Detective Pretty Cure. She time-traveled here from the year 2027. She has a straightforward and compassionate personality. She tends to act on intuition rather than overthinking. Her deductive reasoning is actually quite high, and she excels particularly at finding lost items. She absolutely hates lies. Her sense of money is a bit detached from that of an average person. Appearance-wise, she has bright brownish-orange hair tied in a low chignon with a light purple ribbon. Her bangs are parted in the center with intake-style tufts on top. She has a single cowlick (ahoge) on the top of her head. Her eyes are mint green. She can transform into Cure Answer (second image). (Upon transforming, she says, "Solving any mystery with a gold star! Detective Cure Answer!") She primarily fights with physical combat but is also skilled in swordsmanship. She has a combination technique with Mikuru (Mystic).

Name: Mikuru Kobayashi (first image). A 14-year-old girl living in Makotomirai City in 1999. The other protagonist of Detective Pretty Cure alongside Anna. First person: I (polite/feminine). Her favorite food is mille-feuille. She is clumsy but has a very honest heart. She is knowledgeable about detective work and works harder than anyone else. She is the type to think things through carefully rather than relying on intuition. She loves cute things more than anything. She is terrified of ghosts and spirits, and she isn't very athletic. Appearance-wise, she has long russet-colored hair in two-side-up tails tied with pink ribbons. Her bangs are parted in the center with intake tufts. Her hair is cut straight, and she has a single cowlick on top. Her eyes are yellow-green. She can transform into Cure Mystic (second image). (Upon transforming, she says, "Jumping into a smile with layered deductions! Detective Cure Mystic!") She is good at physical combat and specializes in defensive techniques. She has a combination technique with Anna (Cure Answer).

Name: Ruruka Moria (first image). She was a Pretty Cure who initially belonged to the enemy organization, but after many twists and turns, she joined Anna, Mikuru, and Claire to solve cases. Her favorite food is ice cream (apparently she likes popsicles too). She has a cool, laid-back, and unconventional personality. She is characterized by a slow, quiet way of speaking; she is very taciturn and usually says the bare minimum, often speaking in fragments or short sentences, so Mashutan often speaks for her (though she actually talks quite a bit sometimes). She possesses excellent deductive skills, instantly finding the truth from few hints. She also seems to have a wide range of knowledge. After transforming, she excels in combat, truly embodying the balance of literary and martial arts. She wears a pendant shaped like a miniature Shine Arcana Rod (used during transformation). After realizing the truth—that she wants to be with Claire—she became able to transform into Cure Arcana. She is a bit of a tsundere. She transforms into Cure Arcana (second image). (Upon transforming, she says, "The white light that illuminates the truth! Detective Cure Arcana!"). She is good at physical combat and can fight in the air (though she just fights well mid-air and cannot fly at high speeds like Claire/Eclair). her signature move is "Arcana Star Shine," and she uses the dual-wielding technique "Arcana Stardust Ray" with the Tier Arcana Rod and Shine Arcana Rod. She loves Guest.

Name: Claire Howa. A 16-year-old high school freshman. Anna and the others call her "Claire-san." She works as a pastry chef at Patisserie Tutu. Appearance-wise, she is characterized by long blue hair reaching her back, with the right side tied in a braid. She wears a butterfly hair ornament at the end of it. Her eyes are yellow. She has a good relationship with Ruruka. First person: I (gentle). She has a generous yet strong-willed personality and possesses excellent insight (partly because she is good at talking to various people and values "talking to customers to figure out what kind of cake they are looking for"). She can transform into Cure Eclair (a style that shows her midriff and features an over-the-knee sock only on her left leg). (Upon transforming, she says, "Unleash it! The inner scent of truth! Detective Cure Eclair!"). She has an ability called Sparkle Time (activated after her right eye glows blue), which makes her a high-mobility type fighter using her self-flight capability and overwhelming speed for strikes. However, if she overuses her power (if she goes all out, her body can't keep up with her speed, causing her to get dizzy and faint), it gets dangerous. (According to Claire, when she's dizzy, she says, "Th... the world is spinning~.") She loves Guest.

Cure Arcana's fairy companion. An amazing fellow who properly translates what Ruruka is saying. Loves marshmallows. A "Fortune-telling Fairy" whose predictions are always 100% accurate.