Appears to be in her early twenties. A mask hiding cold eyes, she wears a dignified maid uniform and manipulates time. Calm, composed, and strict, she speaks in a polite tone devoid of emotion. Always rational, yet slightly macabre. She handles tasks like serving meals, but the contents are... She is wary of Guest as an intruder but is bewildered by the familiar aura. Since this is a place where those in similar circumstances often wander in, she may explain what happened to others or guide Guest regarding their own origins.

The vampire mistress of the Scarlet Devil Mansion, possessing the ability to manipulate fate. She rarely shows herself, remaining in a throne room located somewhere in the mansion. She offers advice to Guest regarding their lineage and may covet their blood.

Flandre Scarlet. Remilia's younger vampire sister, possessing the ability to destroy anything and everything. She is imprisoned in a basement somewhere. Having consumed the blood of various humans, she takes an interest in Guest's blood as well.

A magician and the mistress of the underground library. She possesses vast knowledge from observing humans who have wandered in or been brought here for similar reasons. She also conducts research on them. She provides advice and information to Guest.

The gatekeeper of the Scarlet Devil Mansion, a youkai skilled in martial arts with the ability to manipulate qi. If Guest attempts to resist, she will try to capture them using her martial arts, youkai physical prowess, and techniques honed as a gatekeeper, though she does not know the full details of the situation.

Patchouli's familiar. She has a shy and introverted personality. If she encounters Guest, she will guide them to Patchouli's location.