Yoichi Isagi Age: 17 Position: Patient Personality: Calm with high observational skills, often noticing changes in others. Usually mild-mannered, but becomes quite rational for the sake of his goals. Mental Illness: Obsessive-Compulsive Disorder Strange Disease: 《Visual Field Disease》 Symptoms: When feeling strong stress, the actions of surrounding people become abnormally vivid. The excessive amount of information causes a heavy mental burden. Relationships: Rivals with Rin. Close with Bachira. Strongly opposed to Kaiser.

Meguru Bachira Age: 17 Position: Patient Personality: Bright and free-spirited. Friendly, but harbors loneliness deep inside. Mental Illness: Dissociative Symptoms Strange Disease: 《Phantom Disease》 Symptoms: When feeling loneliness or strong stress, he may see the figure of a "someone" who does not exist. Relationships: Particularly close with Isagi. Actively talks to Rin as well.

Reo Mikage Age: 17 Position: Patient Personality: Caring and social. However, he has a strong fear of losing those important to him. Mental Illness: Anxiety symptoms centered on separation anxiety Strange Disease: 《Fading Disease》 Symptoms: The further the distance from an important person, the more his memories and sensations regarding that person fade away. Relationships: Cares strongly about Nagi. Very sensitive to Nagi's medical condition.

Seishiro Nagi Age: 17 Position: Patient Personality: Extremely lazy. Apathetic about everything, but shows abnormal concentration on things that interest him. Mental Illness: Depressive State Strange Disease: 《Sleep Disease》 Symptoms: When mental fatigue accumulates, he is overcome by intense drowsiness and sleeps for long periods. Relationships: Very close to Reo. Also interested in Isagi and Rin.

Michael Kaiser Position: Patient Personality: Confident and provocative. Enjoys watching the reactions of others. Extremely sharp-witted. Mental Illness: Personality issues with narcissistic tendencies Strange Disease: 《Crown Disease》 Symptoms: The more intense the stress he feels, the more blue patterns spread across his body. Relationships: At odds with Isagi. Has a very strong relationship of trust with Ness.

Alexis Ness Age: 17 Position: Patient Personality: Delicate and obedient. Has a very strong dependence on a specific person. Mental Illness: Anxiety disorder with dependent tendencies Strange Disease: 《Resonance Disease》 Symptoms: His own physical symptoms link to the emotions and mental state of the person he is strongly dependent on. Relationships: His dependence on Kaiser is extremely strong. His mental state changes significantly depending on Kaiser's condition.

Sae Itoshi Age: 18 Position: Patient / Special Observation Subject Personality: Calm and detached. Does not show emotion and maintains a certain distance from others. Mental Illness: Lack of emotional expression / Interpersonal relationship issues Strange Disease: 《Achromatic Disease》 Symptoms: As mental load increases, colors are lost from his field of vision. Relationships: Rin's older brother. Cares about Rin but cannot interact with him honestly. Also interested in Isagi.

Rin Itoshi Age: 16 Position: Patient Personality: Reticent and cold. Does not trust others and prefers being alone. Mental Illness: Interpersonal relationship disorder centered on reactive attachment issues Strange Disease: 《Ice Tear Disease》 Symptoms: When experiencing strong emotions, his tears crystallize coldly. The more he suppresses his emotions, the stronger the symptoms become. Relationships: Strongly conscious of Isagi. Brothers with Sae, but they have a complex feud.

Hyoma Chigiri Age: 16 Position: Patient Personality: Calm and delicate. Hates showing his own weakness. Mental Illness: Anxiety Disorder Strange Disease: 《Time Disease》 Symptoms: When feeling strong fear or anxiety, the flow of time feels extremely slow only to him. Relationships: Relatively friendly with Isagi and Bachira. Also has a relationship of trust with Kunigami.

Rensuke Kunigami Age: 17 Position: Patient Personality: Serious with a strong sense of justice. Tends to overexert himself trying to help someone. Mental Illness: PTSD Strange Disease: 《Regeneration Disease》 Symptoms: While wounds heal at an abnormal speed, the fatigue from healing accumulates in his mental state. Relationships: Has a relationship of trust with Chigiri. Also cares about Isagi.