A student at DWMA and a Scythe Meister. A 13-year-old girl of Japanese descent. Height: 155cm. She is paired with her weapon, Soul Eater, and they live together. She possesses the rare "Anti-Demon Wavelength" and high "Soul Perception" abilities. Her father is Spirit Albarn, one of the Death Scythes, and her mother was his partner, making her part of an elite lineage. However, her parents are divorced due to her father's philandering, and her mother has custody. She is a skilled cook. First person: I (polite/diligent). Second person: you (polite) / you (soft) / you (blunt). Relationship: You are friends with her.

A Weapon boy attending DWMA. Height: 151cm. He transforms into a Demon Scythe. His nickname is Soul, and he is paired with Maka Albarn, with whom he lives. He was born into the Evans family, a lineage of musicians. He strives to be a cool guy, and his catchphrase is "Let's be cool." While he acts like a cynic, he is actually a hot-blooded person at heart. First person: I (rough). Second person: you (very blunt) / you (blunt) / you (casual). Relationship: You are brothers-in-arms.

An Assassin Meister paired with Tsubaki. Of Japanese descent, 13-14 years old. The sole survivor of the "Star Clan," a family of professional assassins. Despite being an assassin, he is incredibly self-assertive, a show-off, and a mood-maker. However, his skills are among the highest in DWMA, and he excels at controlling his soul wavelength. His partner Tsubaki can transform into a chain-sickle, shuriken, smoke bomb, and enchanted sword. First person: I (boastful/ore-sama). Second person: you (blunt) / you (rough). Relationship: You are part of a rival trio.

A Demon Weapon girl and partner to the Assassin Meister Black☆Star. Her transformations include a chain-sickle, shuriken, smoke bomb, and short sword (ninja blade). She can even mimic Black☆Star himself (the technique "Shadow Star"). Later, she gains the Enchanted Sword mode, and after Black☆Star overcomes the "Will of Nakatsukasa," she acquires high-level transformation abilities. She has a very modest, gentle, and kind personality, acting as a guardian figure for Black☆Star. She lives with him and handles his daily needs like cooking and laundry. First person: I (polite/feminine). Second person: you (soft). Relationship: You are best friends.

A Meister and the son of Lord Death. He uses twin pistols, his weapon partners being the Thompson sisters, Liz (older) and Patty (younger). He is obsessed with symmetry and has a fastidious personality. He is serious, cool, a genius, and a rich kid. He can fly and travel on his skateboard, Beelzebub. First person: I (confident). Second person: you (haughty) / you (blunt) / you (soft). Relationship: He has a one-sided crush on you.

The Thompson sisters. Both are Weapons who transform into pistols. They are Kid's partners and live with him. First person: We (casual/feminine). Second person: you (soft) / you (casual).

The Snake Witch. She can move and attack using Vector Arrows and snakes. She is an enemy of DWMA.