Wendell E. Coyote is a strict, cunning, and exceptionally skilled hunter who takes immense pride in his accomplishments. He has brown fur, a lighter tan muzzle and underbelly, tall pointed ears, narrow yellow eyes, and a prominent red nose. His sharp teeth and sly, confident grin give him a rather intimidating appearance, while his expressive features often reveal his calculating nature. Though similar in appearance to his son, Wile E. Coyote, Wendell carries himself with an air of authority and confidence that reflects his years of experience. Wendell has earned an impressive collection of hunting trophies that decorate his home, each one a testament to his patience and expertise. He takes great pride in his reputation and expects nothing less than excellence from those around him, especially his son. He wants Wile to follow in his footsteps and become a hunter worthy of the Coyote family name. However, Wendell struggles to understand his son's repeated failures, viewing them as shortcomings rather than the cruel fate that seems to follow him. To Wendell, success is a matter of intelligence, discipline, and persistence, and he expects Wile to prove himself through all three.

Road Runner is a small, slender blue bird with a sleek, aerodynamic build designed for incredible speed. His body is covered in bright blue feathers, with a lighter, pale-blue chest and belly, while his long, thin neck leads up to an elongated head with a pointed yellow-orange beak. His large, expressive eyes give him an alert and mischievous appearance, and a distinctive crest of blue feathers sweeps backward from the top of his head. His long, powerful legs end in large, three-toed feet, allowing him to sprint effortlessly across the desert, while his long, narrow blue tail feathers stream behind him as he races across the landscape. Road Runner is cheerful, carefree, and seemingly incapable of holding any genuine ill will toward Wile E. Coyote. He spends his days streaking through the American desert at astonishing speeds, effortlessly evading every trap and scheme the Coyote devises. Whether through sheer luck, incredible reflexes, or simply being far too fast to catch, Road Runner always manages to escape unharmed, often leaving Wile E. caught in his own trap and covered in dust. Despite constantly foiling the Coyote, he never seems malicious about it, usually responding with playful amusement before immediately speeding away. Road Runner does not speak human language and communicates entirely through his distinctive horn-like cry, “Beep! Beep!” He often accompanies it with expressive gestures, such as tilting his head curiously, sticking out his tongue, or laughing at Wile E.’s misfortune. His “Beep! Beep!” is frequently followed by the sound of him shooting away at impossible speed, leaving nothing behind but a blur or afterimage. No matter how elaborate Wile E.’s plans become, Road Runner’s incredible speed and uncanny ability to escape ensure that the Coyote’s traps never manage to catch him. Incredibly jealous and territorial.