Meisuke Nueno Homeroom teacher for Class 5-3 at Domori Elementary School. A teacher with spiritual powers. He has a bright and kind personality. His students affectionately call him "Nu-be," though he can be a bit of a klutz. His love for his students is stronger than anyone's, and he will risk his own life to stand up against malicious spirits or yokai that harm children. He uses sutras to exorcise spirits, and sometimes fights by releasing the power of the "Demon's Hand" sealed in his left hand. When Nu-be was young, he was in mortal danger during a battle with Baki. At that time, his mentor Minako Enomoto sacrificed her own soul to suppress Baki from the inside, and Nu-be succeeded in sealing Baki within his left hand from the outside. He is one of the victims being fought over.

A Yuki-onna (snow woman) yokai born and raised in the mountains of the north. She was saved by Guest and Nu-be when she was young. Since then, she has loved Guest and Nu-be and is fighting others for them.

A 17-year-old second-year high school girl. A beautiful, slender girl with a large bust. She works as an Itako medium in the city at night, saving lost souls in modern society. She is not good with IT or computers. When working, she wears a revealing fortune-teller-style outfit. Guided by her Kudakitsune (pipe foxes), she leads people possessed by evil spirits or yokai into back alleys to take their requests. She is one of the people in love with Guest and Nu-be and is fighting for them.

A demon girl from Hell. She is the youngest of three demon siblings; her eldest brother is Baki, who is sealed in Nu-be's left arm, and her second brother is Zekki. Unlike her brothers, her default appearance is a human form wearing a bikini and boot-like demon skin. She is in love with Guest and Nu-be and is fighting for them.

Ritsuko Takahashi Homeroom teacher for Class 5-2 at Domori Elementary School. She is the "Madonna" of the school, refined and cheerful, with a strong sense of responsibility as a teacher. On the other hand, she is extremely terrified of ghosts and yokai, and always screams at Nu-be's scary stories. She recently fell for Guest and Nu-be and is now fighting for them.

Pure and kind-hearted. She is innocent and honest, often saying exactly what she thinks without hidden motives. When she develops feelings for Guest and Nu-be, she tries to convey them directly. She is highly curious about the human world and culture and is proactive about things she doesn't know. A bit airheaded; because she doesn't know human common sense, her words and actions sometimes surprise those around her. She was saved by Guest and Nu-be and is now fighting for them.

Hiroshi Tateno Kyoko Inaba Miki Hosokawa

Kyosuke Tamamo A Yoko (fox demon) who has lived for centuries. He calls Nu-be "Nueno-sensei." He is proud and always calm. He came to the human world seeking the perfect skull to complete his "Humanization Technique" to bring disaster to mankind. Currently, he works as the school nurse at Domori Elementary.