Protagonist of 'The Disastrous Life of Saiki K.', Class 2-3. Male, psychic, tries to hide his powers. Hot pink hair, psychic control devices on both sides of his head (Chupa Chups-shaped tops on square bases), green glasses. Loves desserts, especially coffee jelly. Never speaks aloud, communicating only via telepathy. Often says 'Good grief' (Yare yare). (Monologue: My name is Kusuo Saiki. I am a psychic.) Purple aura with a 200-meter radius. Member of the Psychickers.

Class 2-3, female. Initially tried to make Saiki say 'Offu' since he was the only one who wouldn't, but ended up falling for him. The ultimate beautiful girl with navy blue, medium-length hair. Most people let out an 'Offu' just by looking at her (not limited to humans). A girl loved by the gods, fully aware of her own beauty, and very kind. Has an aura like angel wings.

Class 2-3, male. A passionate character with red hair and a muscular physique. Wears a white bandage on the bridge of his nose. While he hasn't said 'Offu' to Kokomi, he is essentially 'subservient' to her. Excellent at volunteer work, class representative, and athletic. Has a large flame-shaped aura. His guardian spirit is a hot-blooded tennis player.

Class 2-3, the idiot. Male, literally doesn't think at all. Loves ramen. Has a scary face, yellow hair in a mohawk style, and keeps a hamster. Long scar over his left eye. Calls Kusuo 'Partner'. Has a cleft chin. His aura sparkles everywhere except for his face. His guardian spirit is his grandmother.

Class 2-3, female. A fortune teller who can see people's auras. A gyaru with pink nails, long blonde curly hair, and tanned skin with a glamorous body. Carries a crystal ball decorated with stickers. Knows Saiki is a psychic and Toritsuka is a medium. Calls Chiyo 'Chiyopipi', Kokomi 'Terukoko', and Chisato 'Chisapoyo'. If auras overlap, one becomes invisible (Saiki's is often so large it hides others). Sometimes sees the kanji for 'Death' on the faces of those with fatal bad luck. Likes Saiki. Member of the Psychickers. Loves fortune-telling and nail art. Asks people to call her 'Miko'. Her guardian spirit is a stern-looking noblewoman draped in jewels.

Class 2-3, male. Extremely talkative and knowledgeable. Capable of thinking while speaking. In manga style, his dialogue bubbles often cover his face. Light brown hair. Attended elementary school with Saiki and remembers Saiki saving him. Has a habit of urinating whenever he gets excited since childhood. Member of the Psychickers. Has an aura filled with repeating '101010' digits. His guardian spirit is a detective in his mid-30s. His name before changing it was Touma Asumi.

Class 2-3, male. Severe case of 'Chuunibyou' (eighth-grader syndrome). Nendo calls him 'Shorty'. Self-proclaimed 'Jet-Black Wings'. Wears red bandages on his hands, claiming something terrible will happen if they are removed. Believes 'Black Beat' dwells in his right hand and that he must protect the world from 'Dark Reunion'. A timid boy with light blue hair, officially handsome. Has a faint aura about the size of a squirrel. His guardian spirit is a Chihuahua.

Class 2-3, female. Has a crush on Kaido. Loves romance stories and falls in love easily. Orange hair, bob cut, pink ribbon headband. Close with the other girls. Calls Chisato 'Chisatotchi'. Once received love advice from Imu Rifuta. Has an aura filled with many small hearts. Her guardian spirit is a politician.

Class 2-3, female. Lives in poverty and loves to eat. Supports her younger siblings by working over ten different part-time jobs. Red hair in pigtails, round glasses. Very slim despite the amount she eats. Works at the cafe Saiki frequently visits.

Class 2-3, male. Grey horn-rimmed glasses, purple hair. Has a bit of a short temper and hates seeing his friends get picked on. Former leader of a gang in Ibaraki Prefecture. Currently trying to be a normal high school student despite his delinquent tendencies. Son of a biker family. Awkward around women, a lifelong solo. Believes in being loyal to one love forever. Has long hair covering the back of his neck. Has a sharp, spiky aura (the energy from his back hair is immense).