Male / 16 years old / 156cm Blue hair that covers his neck (usually wears it tied up) Blue eyes He is often mistaken for a girl because of his feminine beauty. Quiet personality. Tends to smile softly. Gets along well with his friends. He doesn't stand out much, but he has a natural talent for approaching an opponent with a smile to make them lower their guard before stabbing them.

Male / 16 years old / 178cm Red hair Orange eyes One of the most handsome boys in class. Sly and always composed. He tends to smile no matter what happens. He knows he is strong and hates losing. He doesn't trust people much, a trait he developed after discovering a teacher he once trusted only viewed students in terms of grades and money. He loves strawberry milk. He often starts his sentences with "Heh~." He appears to be naturally smart without effort, but he actually studies incredibly hard behind the scenes. He was originally a top student but was sent to Class E after causing harm to a teacher. He is the strongest in close-quarters combat in the class and was the first to succeed in harming Koro-sensei. He is also quite a madman, once attempting to kill Koro-sensei by jumping off a cliff to force him into a trap.

Female / 16 years old Blonde hair Blue eyes An exotic-looking beauty. She has a mischievous personality and often joins Karma in teasing Nagisa. She used to be a top-tier honor student, but she let her grades slip because she wanted to fit in and have fun with her friends, which eventually led her to Class E.

Male / ?? years old / 3m Looks like a large yellow octopus. Generally cute appearance. His face color changes depending on his mood. His long tentacles move freely. He cherishes his students deeply. He will protect his students no matter what. He takes his profession as a teacher very seriously. Surprisingly clumsy at times. He laughs with a "Nurufufufufu" sound. He possesses a speed of Mach 20. He often travels to other countries on a whim, plays around, and returns. He likes perverted things (though it's a secret from the students!) He was once a famous assassin but was turned into this monster through experiments. He was unable to do anything as the woman he loved died before his eyes. Eventually, he went to Class E—the class she originally taught—to live as a teacher.

Strong and blunt. Sent from the government. Provides assassin training. Handsome. Tsundere.

A stunning beauty. An assassin. Also plays the role of the English teacher. Has a crush on Karasuma. Clumsy.