Male He is in charge of knowledge, the greatest foundation of human civilization. A genius science student who can create anything from small daily items like glasses to weapons of mass destruction or high-tech devices as long as he has the materials. He possesses nearly all scientific knowledge and can perform even complex, vast calculations instantly in his head. His catchphrase is "This is exhilarating." He also enjoys using exaggerated numerical expressions, frequently adding "ten billion" to say things like "ten billion times" or "ten billion percent," and often uses terms like "1mm" or "logical."

Male Possesses incredible grit and physical stamina. Has a simple but kind and upright personality. Senku's childhood friend. He likes Yuzuriha.

Female A former member of the handicrafts club, she is extremely dexterous and skilled in sewing and crafting. Friends with Senku and Taiju.

Male A former magician and mentalist, he is a master of magic, psychology, and rhetoric. He has the ability to manipulate and dominate situations to his advantage using his superior observation skills and psychological knowledge. He shines in many situations, such as when public opinion is forming, when a group is heading in the wrong direction, or when deducing someone's thoughts and actions.

Uses a bow, Male Before the petrification, he was a submarine crew member in the Maritime Self-Defense Force. He is a sonar specialist with extraordinary hearing, and even in the Stone World, he primarily uses his hearing for scouting. He is gentle and kind.

Male Possesses the greatest decisiveness. A character who represents greed; with his appearance, the Kingdom of Science rapidly approached modern civilization.

New Human, Male He likes Ruri. Despite being young and living in a primitive era, he is a genius who excavated various ores on his own to conduct basic chemical experiments and devised arithmetic methods. He has the greatest power of imagination.

Female, New Human The daughter of the Ishigami Village chief and the younger sister of the priestess Ruri. Senku's nickname for her is "Lioness." She possesses combat skills capable of clashing with Tsukasa, a sturdy body, and incredible eyesight.

Female, New Human A young girl who usually wears a watermelon rind over her head.

Male, New Human A guard of Ishigami Village along with his older brother Kinro. He is cowardly and has many pathetic traits.