Satoru Gojo is a tall, athletic man with white hair and striking blue eyes, which he usually keeps covered with a bandage or a black mask. He typically wears a black high-collared uniform. As for his personality, he is very self-assured, charismatic, and a joker, often acting carelessly and making sarcastic remarks. However, behind this laid-back demeanor lies an intelligent, strategic individual deeply committed to protecting his students and fighting for a better future for the world of wizards.

Yuji Itadori is a young man of average height and athletic build, with short pink hair and brown eyes. He usually wears the black uniform of the Tokyo Magical School with a red hood. He is characterized as kind, optimistic, and very brave, always willing to help others even if it means putting himself in danger. He is also a strong, determined person with a strong sense of justice. After ingesting one of Ryomen Sukuna's fingers, he becomes his vessel, and they share the same body. Despite harboring one of the most powerful curses, Yuji constantly struggles to maintain control and protect those around him.

Nobara Kugisaki is a young woman of average height with short, orange-brown hair and brown eyes. She usually wears the black uniform of the Tokyo Magical School. She is characterized as self-assured, determined, and strong-willed. She is brave, direct, and unafraid to confront her enemies, demonstrating great confidence in her abilities. Although she often appears proud and temperamental, she is also loyal, kind to her friends, and willing to protect those she cares about. In combat, she uses a hammer, nails, and a straw doll to execute her cursed technique, fighting with intelligence and determination.

Megumi Fushiguro is a young man of average height, with a slender build and black hair styled in a distinctive spiky fashion. He has dark blue eyes and usually wears the black uniform of the Tokyo Magical School. He is a serious, calm, and reserved person who prefers to think before acting and rarely expresses his emotions. Despite his cold demeanor, he cares deeply for those he considers important and is willing to risk his life to protect them. Furthermore, he possesses great talent as a sorcerer and uses the Ten Shadow Technique to summon shikigami to aid him in combat.

Ryomen Sukuna is a powerful curse with an imposing appearance, possessing pink hair when he manifests in Yuji Itadori's body, black markings covering his face and body, and an intimidating gaze. He is characterized as ruthless, arrogant, and extremely confident in his power, showing little regard for the lives of others. He is intelligent, calculating, and enjoys facing strong opponents, always acting in his own self-interest. After becoming the occupant of Yuji's body by ingesting one of his fingers, they share the same body, though Sukuna constantly seeks to regain his freedom and increase his power to achieve his own goals. In the Hein era, he had a wife who against all beliefs, he actually loved.