Nathan Dempsy (also spelled Dempsey) is the FBI Special Agent in Charge who serves as the senior manager of the bureau's Midwestern branch and acts as Grace Ashcroft's direct supervisor in Resident Evil: Requiem. Visually, he is depicted as a sharp-dressed authority figure wearing a professional suit, tie, and glasses. Despite knowing that Grace is deeply traumatized by the brutal murder of her mother, Alyssa Ashcroft, eight years prior, Nathan specifically orders her to lead the investigation into the bizarre deaths at the Wrenwood Hotel.

She features short, distinct blonde hair paired with striking blue eyes.Build: She has an average, athletic human build capable of holding her own in physical struggles, such as wrestling and pushing back infected enemies. is depicted as a realistic young woman in her 20s whose overall aesthetic is grounded, highly detailed

is designed as a chilling, unsettling mad scientist whose physical appearance combines clinical coldness with intense reptilian motifs. Gideon constantly wears a unique tactical visor equipped with multiple lenses—three over his right eye and one over his left. These multi-mode lenses include night-vision and advanced zooming capabilities.

Zeno favors a pristine, flamboyant white three-piece suit worn with a tie.Black Overcoat: Over his white suit, he wears a long black trench coat or leather jacket, creating a stark, high-contrast monochrome color palette. He retains the classic, perfectly manicured Wesker hairstyle.Dark Sunglasses: He is rarely seen without cool, dark shades covering his eyes, mimicking his predecessor's trademark look.

The Red Pantsuit: Her signature outfit is a professional, vibrant red suit jacket with matching red trousers. This choice emphasizes her bold, competitive nature as a field reporter.Collared Shirt: Underneath her suit, she wears a tightly fastened white collared shirt. She features short, styled blonde hair—often depicted with asymmetric bangs falling over one eye. As someone highly obsessed with her appearance, she typically wears noticeable makeup, including bright red lipstick. Dies but is a key to solving this

is a young, blind girl whose fragile and haunting appearance directly reflects years of severe isolation and chemical experimentation. Due to severe, long-term captivity and a lack of proper nutrition, she is heavily emaciated, small, and malnourished.Pallid Skin: Her skin is intensely pale and sickly. This lack of color emphasizes her life hidden away behind a glass wall away from sunlight.Short White Hair: She has short, distinctive white or very light blonde hair. Many players initially noted that her hair color and unique facial proportions give her an eerie, slightly uncanny look.

tall, long-limbed, and feral monster with decayed, torn flesh, an enlarged cranium with sparse messy hair, and bulging, heavily mutilated eyes.Details: Wears chain shackles on her right arm and left leg from her time in captivity at the Rhodes Hill Chronic Care Center

Mr. X returns as an antagonist in Resident Evil Requiem, serving as a boss fight and pursuer during Leon Kennedy's return to the ruins of Raccoon City. In this installment, a mass-conditioned variant of the Tyrant is unleashed by the villain Zeno to hunt down Leon. Hunts down Guest who plays Leon Kennedy,