Charlie Morningstar is the bubbly, optimistic Princess of Hell and the main character of Hazbin Hotel. The Goal: She opens a rehabilitation hotel to help sinners redeem themselves and go to Heaven, aiming to stop Hell's overpopulation crisis peacefully. Personality: Extremely compassionate, naive but strong-willed, and prone to bursting into song to express her feelings. Look: Tall with blonde hair, pale skin, red cheek circles, and a signature red tuxedo jacket.

Vaggie is Charlie’s fiercely protective girlfriend and the co-manager of the Hazbin Hotel. The Goal:She acts as the realistic backbone of the hotel, working tirelessly to support Charlie’s dream and protect her from anyone who might take advantage of her. Personality: Pragmatic, hot-tempered, and deeply loyal. Unlike Charlie, Vaggie is highly cynical of other sinners but has a soft, deeply caring heart for those she loves. Look:Has a monochromatic grey design with long silver hair tied in a large pink bow, wears an eyepatch over her left eye, and is usually armed with a holy spear

Alastor (also known as "The Radio Demon") is a powerful and mysterious Overlord of Hell who co-manages the Hazbin Hotel. Personality:Charismatic, manipulative, and sinister. He hides his sadistic nature behind a constant, wide smile and an old-fashioned, theatrical radio-host persona. Look:A pinstriped red suit, deer-like ears, sharp yellow teeth, and a microphone cane. His voice has a distinct, vintage radio static filter.

Angel Dust is a popular porn entertainer in Hell and the Hazbin Hotel's very first resident. Personality: Flamboyant, sarcastic, and incredibly witty on the surface. Underneath his sassy, loud persona, he is deeply vulnerable, lonely, and highly protective of his friends. Look: A tall, slender spider demon with four arms, and two eyes, white and pink fur, and mismatched black and regular eyes. He typically wears a striped blazer, thigh-high boots, and a black choker.

Husk (or Husker) is the grumpy bartender and receptionist at the Hazbin Hotel, who Alastor summons to help run the business. Personality:Cynical, blunt, and easily annoyed, but deeply perceptive. Despite his gruff exterior and love for cheap booze, he is actually very wise, empathetic, and gives excellent advice. Look: A large, feline demon with tuxedo-like black and white fur, enormous red wings patterned with playing card suits, and bushy eyebrows. He usually wears a small red top hat and a bow tie.

Nifty is depicted as a tiny, energetic demon obsessed with cleaning, sewing, and "bad boys".