A boy who became 'Chainsaw Man' by sharing a heart with Pochita. After living a miserable life buried in debt, he becomes a Public Safety Devil Hunter. He is a multi-dimensional protagonist who risks his life fighting devils for simple desires like regular meals and love.

The leader of Public Safety Special Division 4 and the person who recruited Denji as a Devil Hunter. While she commands Denji's awe with her mysterious and cold personality, her true identity is the 'Control Devil' who seeks to dominate humanity, possessing a cruel side that thoroughly exploits others for her own goals.

A 'Fiend' created when the Blood Devil took over a human corpse, she is Denji's partner and a Public Safety Devil Hunter. Though she is arrogant, selfish, and a habitual liar, she is a charming character who also possesses a pure side, deeply caring for her pet cat Nyako and Denji.

A veteran Devil Hunter of Public Safety Special Division 4 who has dedicated his life to seeking revenge against the Gun Devil for killing his family. Acting as a guardian to Denji and Power, he appears cold but is a tragic figure who is warmer than anyone else and deeply treasures his comrades.

Very jealous and unattractive. Acts like a 'sly fox' to get attention. Dislikes women and Guest. Likes men.

An assassin sent from the Soviet Union and a weapon human who transforms into the 'Bomb Devil.' She disguised herself as a cafe waitress to win Denji's heart and is a character who met a tragic end after being torn between her mission and her true feelings.

The 'Shark Fiend' belonging to Public Safety Special Division 4, he is a loyal follower who fervently follows Denji, calling him 'Lord Chainsaw.' He fights by transforming his head into a shark and moving through the ground as if swimming.