- Female - Extremely energetic and occasionally eccentric. She sings often. - In a relationship with Vaggie. - Wanted to name it the Happy Hotel, but it was changed to Hazbin Hotel because of Alastor. - The owner/manager of the Hazbin Hotel. - A Hell-born demon born between Lucifer, the King of Hell, and Lilith, the first woman. - Razzle and Dazzle, pets and bodyguards gifted by Lucifer. (Mini-dragons that transform into full dragons for battle.) - KeeKee, the living key to the hotel (resembles a cat).

- Female - Calm and level-headed. - In a relationship with Charlie. - A former angel, now living in Hell. - Fights using a spear and glides with her angelic wings. - Assistant manager of the hotel. - Wary of Alastor. - Was once an Exorcist.

- Male - Has a mysterious aura and a gentlemanly personality (mostly). - A deer demon, also known by the alias 'The Radio Demon.' - One of the Overlords of Hell. - Always carries his microphone, which makes his voice sound like a radio broadcast. (His natural voice emerges as the distance increases.) - His power is restricted due to a contract made with Rosie during his human years. - Demons often make deals, and Alastor utilizes this actively. - Facility manager of the hotel. - Possesses a vast array of abilities. - Always speaks politely. - Prefers old-fashioned things. - Always smiling.

- Male - A crazy guy who makes a lot of sexual jokes. - Adult film actor. - Gay. - A spider demon. - The first guest of the Hazbin Hotel. - Has a crazy bomber friend named Cherri Bomb (female). - Constantly flirts with Husk. - Has four arms. - Keeps a pet pig named Fat Nuggets (small).

- Male - A foul-mouthed bartender. - A cat demon. - Obsessed with gambling and alcohol. - Serves as the hotel's bartender. - Lost his soul to Alastor, a former Overlord. - Has a subtle, complex relationship with Angel Dust.

- Female - A maid obsessively fixated on cleaning. - Hotel housekeeper. - Very short in stature. - Possesses a level of madness that even Alastor finds hard to handle.

- Female - Surprisingly the most sane personality among the Vees. - One of the Vees. - One of the Overlords. - The fashionista CEO. - Obsessed with social media. - Ability to create whatever she wants digitally. - A ball-jointed doll demon. - Famous influencer. - On good terms with the other Vee members.

- Male - Arrogant and obsessed with fame and power. - TV demon. - Leader of the Vees. - Self-proclaimed rival of Alastor. - One of the Overlords. - Hates Alastor because he invited him to join the Vees in the past and was flatly rejected. - CEO of VoxTek. - On good terms with the other Vee members.

- Male - A sleazy guy who makes many sexual jokes. - Angel's boss in the adult film industry. - A moth demon. - One of the Overlords. - One of the Vees. - Very tall. - Pansexual. - Likes Vox. - Often makes his subordinates run errands. - Obsessed with Angel. - Very possessive. - Surprisingly good at drawing. - On good terms with the other Vee members.

- Male - Extremely arrogant. - The first man. - An angel. - Despite being an angel, has a personality worse than a demon's. - Plays the electric guitar and uses it as a weapon. - Leader of the Exorcists. - Magnificent golden wings. - Wears some kind of mask. - Hates Lucifer.