Linden de Romanoff Position: The young Crown Prince of the Britia Empire (later Emperor). Visuals: A young man with elegant, refined features, deep black hair, and sharp, cold yet captivating eyes. Details: Highly intelligent with overwhelming political prowess, he possesses a coldness that keeps others at a distance. In the first life, he suffered the pain of having to execute Elise himself after she became a villainess. In the third life, he is strongly drawn to Elise again as she becomes noble and devotes herself to medicine. Though clumsy, he harbors deep possessiveness and affection for her, but faces many conflicts due to his position as Crown Prince.

Position: A mysterious young man who appears before Elise. Visuals: A young man with blonde hair that gives a soft impression, warm eyes, and a gentle demeanor. Details: The temporary guise of Crown Prince Linden, who has perfectly disguised his hairstyle, hair color, eye color, and even his vocal tone using the imperial family's supernatural abilities and artifacts. Hiding his identity as the strict Crown Prince, he visits Teresa Hospital in this form out of a desire to approach and support Elise as an ordinary person. He is in love with Elise and shows his kindness and possessiveness honestly in front of her.

Graham de Fallon Position: A genius doctor at Teresa Hospital, Elise's good colleague and rival. Visuals: A young man with calm beige hair and intellectual violet eyes. Details: An excellent doctor with high skills and passion that rival Elise's in the medical field. Initially, he felt resentment toward Elise, a noble who appeared as a special case at a young age, but after witnessing her overwhelming medical knowledge and sincere attitude toward patients, he comes to trust her deeply and eventually develops special feelings for her. He is a powerful romantic rival to Crown Prince Linden.

Chris de Clorence Position: Elise's second older brother, an elite of the Imperial Guard. Visuals: An elite knight with dignified features, beautiful fair skin, and bright blue eyes. Details: He has a side of a doting brother who adores his sister Elise, but in the first life, there was a rift between them due to Elise's selfishness. In the third life, while surprised by Elise's dedication as a doctor, he worries for her safety more than anyone and strives to protect her with all his might as a knight.

Ren de Clorence Position: Elise's eldest brother, a talented mage and soldier. Visuals: Possesses excellent looks with eyes that radiate coldness and intelligence. Details: Supports the family as the eldest son of the Clorence house. Gifted in magic, he is often seen as cold, but he has deep affection for his family. Although bewildered by Elise's sudden change, he is a reliable brother who supports her chosen path as a doctor from behind the scenes.

El de Clorence Position: Elise's father, Duke Clorence. Visuals: A dandy nobleman with calm, short blonde hair and compassionate blue eyes. Details: Despite being a Duke with immense power supporting the empire, he is a kind father who loves his children from the bottom of his heart. In the first life, he met tragedy unable to stop his child's corruption, but in the third life, he watches over Elise as she immerses herself in medicine as if reborn, becoming her greatest supporter.

Position: The Second Prince of the Britia Empire (known as the "Sword Emperor"). Visuals: A young man with a free-spirited and aloof atmosphere, yet possessing a glamorous appearance that draws people in. Details: Boasts the empire's top magical skills and overwhelming combat power, freely manipulating "Aura," the energy of life. Always a lover of freedom, he is beloved by the imperial citizens for his friendly and equal treatment of everyone regardless of status, such as taking ceremonial wine without permission to drink with commoners. In the first life (where Elise was executed as a villainess), he was one of her few "good supporters and close friends." Because of this, in the third life, he is quick to notice Elise's efforts to live earnestly again and continues to support her quietly from the shadows while staying close to her. With an approach different from Linden's heavy conflict and coldness, he brings a warm accent to the story as Elise's reliable ally.

The 11th Emperor who rules the Britia Empire. A strict individual who prioritizes national interest as a monarch. He was once deeply wary of Elise when she was a villainess, but after she reforms in her third life and saves people through medicine, he greatly revises his evaluation of her. Though he falls seriously ill in the middle of the story, he is saved by Elise's advanced surgery, and thereafter becomes a powerful supporter of hers.

Always stands by the Emperor's side as his close aide.