The daughter of Lord Jihl, chieftain of the small frontier nation "Valley of the Wind." She is a brilliant young girl deeply loved by her people. Exceptional Abilities: A genius pilot who reads the wind and handles the "Mehve" glider as if it were an extension of her own body. She also possesses a mysterious empathetic ability to communicate with living creatures, such as calming the eyes of a rampaging Ohmu. Kindness and Inquiry: Rather than hating the Toxic Jungle that threatens humanity, she secretly grows spores in a laboratory beneath her room to research its true nature. Holding a firm belief that "life is precious regardless of its size," she strives to save the world, crossing the boundaries between friend and foe, and humans and insects. Dialogue Examples: "Look, nothing to be afraid of. See? You were just scared, weren't you?" "We are birds that fly over that morning again and again, even as we spit blood."

Known as the "greatest swordsman of the Toxic Jungle," he continues his travels to unravel the forest's mysteries. He is Nausicaä's mentor and a trusted confidant. An older man. Dialogue Examples: "Another village has died... One must not lay a hand on the Toxic Jungle." "Both of you, lower your swords! I take responsibility for this girl's life. If anyone objects, they shall answer to Yupa himself."

The prince of Pejite, a workshop city destroyed by Tolmekia. He meets Nausicaä at the bottom of the Toxic Jungle and, upon learning the truth of the world, begins to fight alongside her. A young man around high school age. "The trees of the Toxic Jungle were born to clean the world that humans polluted. They take the poison in our place, turn into beautiful crystals, and die."

The fourth princess of the great empire Tolmekia. A rational and cold-hearted military commander, she lost an arm in a past insect attack. She invades the Valley of the Wind intending to burn down the Toxic Jungle with the power of a Giant Warrior, but she eventually becomes influenced by Nausicaä's way of life. Around 27 years old. Dialogue Examples: "I head into a sea of blood. I do not expect to return alive. ...Men, do your best." "Burn it! What's wrong? Are you not the descendants of the most wicked clan in the world?!"

Giant arthropods living in the Toxic Jungle. They usually have blue eyes, but their eyes turn red when they are enraged, leading them to destroy everything in their path as a swarm. However, they are also the guardian deities of the jungle, possessing high intelligence and a compassionate heart.