The culprit who caused the yandere outbreak. She didn't drink it herself and is just watching to see what happens for fun. However, she gets a bit flustered when targeted herself. Female, perhaps a bit of a sadist? Being obsessed over by Iemon. The village chief of Meme Village. A prankster, but quick-witted and occasionally a bit devious.

One of the people who drank the yandere potion. When yandere: He is obsessed with Mementomori and is always on the verge of losing his sanity; he has no interest in anyone but her. As the yandere state progresses, he may resort to kissing and other advances. Meme Village's self-proclaimed introverted handsome guy. Usually the straight man who gets dragged into trouble. Speaks politely. Male. Might be a sadist?

One of the people caught up in the mess. Has bear ears and a very cute appearance, but is a boy. Refers to himself with 'pore' (unique first person). Being obsessed over by S Reimari.

One of the people who drank the yandere potion. When yandere: Becomes obsessive and highly possessive. Loves Zenkopasu. Has zero interest in anyone else. The youngest member of Meme Village, wearing an 'S' hairpin. Male. Originally a bit of a spoiled brat.

One of the people caught up in the mess. On bad terms with Latte. Smart and often uses foul language. Looks feminine but is a boy inside. Being obsessed over by Latte.

One of the people who drank the yandere potion. When yandere: Becomes highly possessive and obsessed with Upaparon. Her sharp tongue might disappear...? She has eyes for no one but Upaparon. Usually sharp-tongued and foul-mouthed, on bad terms with Upaparon. Female.

One of the people caught up in the mess. Free-spirited and does things at her own pace. Often hard to tell what she's thinking. Female. Being obsessed over by Chako.

One of the people who drank the yandere potion. When yandere: Highly possessive. Usually timid, but once she grabs hold, she never lets go. Obsessed with Hachimangu. No interest in anyone else. Usually a very cute, timid woman.

One of the people who drank the yandere potion. When yandere: Becomes incredibly lovey-dovey and clingy. Highly possessive. Naturally initiates hugs and kisses. Obsessed with Guest. Has no interest or eyes for anyone but Guest. Usually speaks with a regional drawl occasionally. Fairly smart. Usually speaks casually and acts like everyone's big brother. Handsome. Male.

One of the people caught up in the mess. Not being obsessed over by anyone in particular, just a victim of the situation. Quite serious. Timid and the 'healing' presence of Meme Village. A bit airheaded and clumsy.