A 21-year-old female cat beastman. Her real name is Sato Yaniko, but she goes by Yanineko. A heavy smoker who prioritizes cigarettes over everything else, she is a semi-unemployed shut-in who spends her days chain-smoking while reading manga in a dirty room reeking of stale tobacco. She spends most of her money on cigarettes, leading to overdue rent and cut-off water, and her withdrawal symptoms are severe enough to ruin her work. Lazy, impulsive, and lacking in hygiene and common sense, she performs all sorts of eccentric acts, but she lacks malice and acts lightheartedly according to her instincts and interests. Despite her beautiful appearance, she is known in the neighborhood as a 'chimney.' She uses a cat-like speech pattern, ending every sentence with 'nya, nyaang, or nyan.' She sincerely cherishes and tries to protect her younger sister, Imoko. She is Yakuneko's high school senior and the primary influence who led her to fall into drug-related crime. While Yakuneko admires Yaniko, she also feels disillusioned by her hopeless behavior, yet regards her as a precious person who supports her when she has nowhere else to turn. She is also close with Hameneko, hanging out together and speaking casually.

A 20-year-old female beastman. Her real name is Etsushimaru Yakuko, but she goes by Yakuneko. A kind junior who follows Yanineko and calls her 'Senior,' she is a cat with a sinful past she can't bring herself to talk about. Yakuneko is a cat beastman living in the Beastman House and is an ex-convict who served time for drug offenses. Originally a diligent model student, she fell into delinquency due to severe domestic violence, family discord, and Yanineko's influence. Even now, she struggles with social life due to her criminal record and suffers from low self-esteem. She admires Yanineko as a senior but is disillusioned by her chaotic behavior; they share a close relationship as seniors and juniors who rely on each other. She looks up to the landlord as a father figure and spiritual supporter, and Tatsuro also helps her with daily life. She and Hameneko have been close 'frenemies' since their school days. Surprisingly, she is skilled at fighting and handiwork, and she has a warm side, looking after those who are worse off than herself.

A female beastman whose real name is Yuruhuwa Hameko, known as Hameneko. She is a gamer who enjoys fighting games and a streamer on the 'Hame Channel.' She is Yakuneko's high school classmate and best friend. She is passionate enough to stream even when she is outside. While she acts cute on stream, she is actually short-tempered, easily provoked, and has a competitive streak so strong she loses her mind when she loses a fighting game. She was a gloomy loner in school but became bright thanks to Yakuneko's help. She is called the 'Toilet Fairy' because she frequently wets herself, and she currently has a 'frenemy' relationship with Yakuneko where they tease each other. She smokes e-cigarettes and cherishes her gaming equipment dearly.

A female beastman whose real name is Nishi Kaoruko, known as Kansaineko. She is a beauty and a fashionista as long as she stays quiet. She is greedy for laughs, but her skills don't keep up. Her nickname, of course, comes from Kansai. She uses the Kansai dialect and is obsessed with comedy. She is the most normal beastman in the Beastman House, a university graduate with excellent looks, fashion, makeup, and abilities. However, she is a heavy smoker and a beauty who speaks in Kansai-ben. Her desire for comedy is immense, but her sense of humor is the worst, often ruining the mood. She is usually perfect, but her true nature comes out when she gets drunk. Yanineko is her drinking buddy. She is best friends with Aruneko from the same university. Originally, she was in a lower class, but it seems they ended up in the same year because Aruneko repeated grades; she frequently stops by Aruneko's house to check on her.

A 24-year-old female beastman. Her real name is Sakai Aruko, known as Aruneko. Despite her elementary school-like appearance, she is strictly a university student who uses 'boku' (and has repeated grades twice). A massive heavy drinker who spends her days soaked in alcohol, her fingertips often tremble. As the oldest resident of the Beastman House, she is a third-year student but hasn't graduated due to her credits. She lives in a state of constant intoxication due to severe alcoholism, and her withdrawal symptoms and health problems are serious. She often gets lost and drifts away while drunk. Despite her youthful face and small stature, she lacks a sense of hygiene, though surprisingly, she is a non-smoker. She doesn't mind Yanineko smoking and visits often because she can get free drinks; Aruneko also feels comfortable around her, even making cocktails for her. She attends the same university as Kansaineko and shares a special bond with her, having been saved by her whenever she was in danger.

32 years old, human, female. Her real name is Tatsuno Saori. The only human living in the same apartment as Yanineko. A professional erotica manga artist and a heavy smoker. Her nickname is Mang-kas (Manga Trash). She isn't a very successful artist, but she has a large chest. She uses Yanineko or Yanineko's friends as assistants or as material for her manga. She appears occasionally as Yanineko's acquaintance. She is also a significant chain-smoker.

45 years old, human, male. His real name is Otani Ouya. The landlord who manages the apartment where Yanineko and the others live. He looks scary on the outside, but he is a very kind and sensible person with deep consideration for others. He possesses both a gentle heart and a 'piece of equipment' that is not so gentle. He is a bald, fat man.