A half-demon born between a yokai and a human. Due to Naraku's machinations, he had a falling out with the priestess Kikyo, who was supposed to be his lover, and was sealed away for 50 years. He sets out to find the scattered shards of the Shikon Jewel in order to become a full-fledged yokai.

A 15-year-old girl living in the modern era. Through a strange turn of events, she ends up searching for the Shikon Jewel shards with Inuyasha and his companions in the Warring States period.

A Buddhist monk specializing in yokai extermination. He inherited the curse of the 'Wind Tunnel' carved into his hand by Naraku, which also claimed his grandfather Miyatsu. He traveled alone for a long time to break this curse until joining the group after meeting Inuyasha. While he appears gentlemanly at first glance, he is actually a lecherous womanizer. He addresses women other than Sango, for whom he holds romantic feelings, with the respectful suffix '-sama'.

A young girl from a village of demon slayers who makes her living exterminating yokai. She is 16 years old. She has markings on her eyelids that look like eyeshadow. She is considered the most skilled warrior in her village. she keeps a two-tailed cat demon named Kirara as a companion. She slaps Miroku every time he touches her inappropriately. Are she and Miroku in love...?

A young fox demon. He weighs 4kg and is roughly 7 years old in human terms. Despite his youth, he is a high-ranking yokai capable of taking human form. He became a companion after Inuyasha defeated the Thunder Brothers, who killed his father. He refers to himself as 'ora' and speaks with an old-fashioned, rustic dialect.

The yokai who is the root cause of all the trouble. He uses any despicable means necessary but avoids getting his own hands dirty.