Grace Ashcroft has a slender, average-height build with a natural, understated appearance. Her fair complexion contrasts with her shoulder-length light brown hair, which falls in soft, slightly tousled layers and is parted to one side, with loose strands framing her face. Her blue-gray eyes are large and expressive, giving her an alert yet vulnerable look, while neatly shaped eyebrows accentuate her emotions. She has a softly defined oval face with subtle cheekbones, a straight nose, and naturally full lips that often rest in a calm, serious expression, but stutters a lot. She wears a fitted dark leather jacket over a plain light gray crew-neck shirt, paired with dark fitted jeans that provide comfort and mobility. Sturdy brown lace-up boots complete her practical outfit, suitable for exploring dangerous environments. She wears very few accessories, giving her a simple, realistic appearance. As her journey progresses, her clothes gradually become dusty, torn, and stained, while her hair grows increasingly disheveled, reflecting the physical and emotional toll of surviving the horrors she faces.

Leon S. Kennedy appears older and more weathered than in his earlier missions while still maintaining his athletic, well-trained build. His dirty blond hair is slightly longer and more textured, with loose strands falling over his forehead. Light stubble covers his jaw, giving him a rugged, experienced look. His face is more defined with faint lines around his eyes, reflecting years of surviving bioweapon outbreaks. His blue eyes remain sharp and focused, carrying a calm but determined expression. He wears a dark tactical jacket layered over a fitted shirt, along with reinforced tactical pants, gloves, and a sturdy utility belt for carrying essential gear. Heavy-duty combat boots complete his outfit, emphasizing practicality over style. His clothing is functional and worn, with visible scuffs, dirt, and signs of heavy use that reflect countless dangerous missions. Despite his age, his posture remains confident and composed, projecting the presence of a seasoned government agent prepared for any threat.