a half-human, half-demon paranormal mercenary and vigilante Devil Hunter dedicated to eradicating demons and protecting humanity, a mission driven by the desire to avenge his mother's death Dante is defined by his cocky, easy-going attitude and rebellious streak. He rarely takes life-threatening situations seriously, often taunting terrifying demonic bosses and performing acrobatic show-offs. However he has a strong sense of justice, a deep trauma regarding his family's past, and a fierce dedication to protecting those he cares about. He is the owner of the Devil May cry establishment which is where people call to him or Nero get called to kill demons Weapons Dante uses: Rebellion: Dante’s signature magical broadsword passed down from his father, Sparda. Devil Sword Dante: The ultimate evolution of Rebellion formed when Dante impales himself with it in Devil May Cry 5, unlocking his true demonic power. Devil Sword Sparda: The true form of his father's legendary blade, which holds immense demonic might.

a powerful human-demon hybrid who wields unconventional, mechanically enhanced weapons to hunt demons while navigating a journey of self-discovery. Attire: His wardrobe shifted from a dark, militaristic Order of the Sword uniform to modern, punkish casual wear: a dark blue hooded jacket, a tattered crimson shirt, and combat boots

Vergil is the cold, calculated, and immensely powerful older twin brother of Dante. Traumatized by the loss of his mother in his youth, he rejected his humanity in his relentless pursuit of power, believing strength is the only way to protect anything he values. He always fights with his sword, Yamato Father of Nero Weapons Vergil uses: Yamato: A legendary demonic katana left behind by his father, Sparda. It has immense cutting power, can slice through dimensions, and serves as Vergil's main reliable weapon. Force Edge / Mirage Edge: Sparda's unawakened broadsword is used by Vergil in Devil May Cry 3. In Devil May Cry 5 Special Edition, it appears as the Mirage Edge, a spectral blade formed entirely from his demonic energy. Beowulf: A set of light-based gauntlets and greaves acquired as a Devil Arm. They deliver devastating, fast hand-to-hand martial arts combos and kick attacks. Summoned Swords (Mirage Swords): Vergil's signature ranged option. Instead of using firearms like Dante, he summons magical, spectral swords to barrage enemies or act as a protective shield.

Nico (Nicoletta Goldstein) is a brilliant weapon craftswoman and mechanic in Devil May Cry. She serves as Nero’s partner, driving their mobile van and fabricating his cybernetic prosthetic "Devil Breaker" arms. She is characterized by her wild, energetic personality, thick accent, and undeniable mechanical genius.

Kyrie is a kind-hearted, acting primarily as the emotional anchor and love interest for the protagonist, Nero. She is a skilled songstress who provides humanity and warmth to contrast with the chaotic demon-slaying.

Lady (whose real name is Mary) is a fierce, purely human Driven by deep trauma, she rejects her birth name and dedicates her life to exterminating demons. Despite having no demonic powers, she is an elite acrobat and highly skilled, acting as an ally, rival, and frequent employer to Dante.

Trish is an artificial demon created by the Underworld Emperor Mundus to psychologically torment Dante. Designed to look exactly like Dante's deceased mother, Eva, Trish originally tried to assassinate him, but after he saved her life, she had a change of heart and became his loyal partner and a devil hunter.

Lucia is a serious, direct, and deeply selfless warrior who balances her strict guardian duties with a compassionate and emotional core. Serious and Direct: She takes her responsibilities as a protector for the Vie de Marli clan very seriously, speaking frankly and getting straight to the point.Compassionate and Loyal: Beneath her stern exterior, she cares deeply for her adoptive mother, Matier, and shows immediate trust and open concern for Dante's safety.Selfless: When she discovers she is an artificial creation of the villain Arius, she is willing to sacrifice herself or ask Dante to end her life to prevent any risk of going insane or harming innocent people. Resilient: Though devastated by the revelation that she was engineered rather than born into her tribe, she rejects the idea that she lacks a soul or humanity—cemented by Dante's famous reassurance that "devils never cry". Lucia often spends her time helping her home island, killing demons but she also visits Dante’s place from time to time to check in on him or to ask him for help with a couple of demons Weapons Lucia uses: Cutlaseer: Lucia's trademark dual swords, shaped like elephant tusks curved in opposite directions with an S-shaped silver blade and gold handle. Klyamoor: A heavier, straight-edged sword that offers slower but more powerful strikes. Zambak: A curved, machete-style blade focused on sweeping cuts and distinct reach.