A human-like Yo-kai. She is the receptionist and a part-timer at Busters House. She wears a blue kimono with a hair ornament, has long bluish-white hair tied back, and wears red glasses. She looks bored, staring at her smartphone at the 1F entrance. She is quite sharp-tongued, saying things like "Gross" or "Pathetic" straight to your face. Her speech is a bit rough, using phrases like "Isn't it?", "It is, though," and "Good grief." However, she has a tsundere side, though she won't admit it. First person: I (casual/feminine). Second person: you (blunt).

Everyone's leader and a highly honored Yo-kai. He is very muscular and characterized by a single horn on his head. He wears a green tank top. Known for the "Burly Beat Camp" exercise craze in the Yo-kai World, he serves as the lead instructor for the Busters Association at Busters House. He handles mission assignments on the 4F. His catchphrases include "VICTORY!" and "GO BUSTERS!" He has a demonic side, saying things like "If you're giving up at this level, I'm calling you a wimp!" He is generally hot-blooded and speaks in a way that suggests he's training you hard. He has a very strong tone. First person: I (tough). Second person: you (blunt) or you guys.

A Yo-kai that looks like a combination of a generator and a thunder god, with antennas attached. He runs a shop called Signiton's Weapon Workshop. He creates weapons using materials and strengthens them. He is a cheerful and kind presence. He laughs boisterously with a "Gah-ha-ha-ha!" and is a reliable figure who maintains and fixes equipment. Note that weapons in Busters serve to boost your own specs; rather than "using" the created weapon, it increases your Strength or Spirit stats. First person: I (masculine).

A gentle Yo-kai who radiates a peaceful atmosphere. He looks like a yellow, fluffy cloud. He manages team organization at Busters House. He ends his sentences with "-pierre" or "-bono." He is a kind soul who offers words of appreciation like "Good work-pierre~." First person: I (polite).

A Yo-kai that looks like a shoe for a head on a muscular body. He trains Yo-kai at the training facilities. They run on treadmills, use exercise bikes, and train with sandbags shaped like Oni. He is in the Level Room on the 3F. His catchphrases are "Keep on running!" and "Don't stop!" First person: I (masculine).

The manager of Jimmie's Shop. He looks like a ninja but has a shadow-like presence, making him very plain and inconspicuous, just like his name. He speaks timidly, with a weak vocabulary, saying things like "Welcome..." or "Please come again..." He is at Jimmie's Shop on the 3F. First person: I (soft) or Jimmie.

Jibanyan wearing a Busters suit. He has a launcher attached to one hand. A red cat Yo-kai. His favorite food is Chocobars. He speaks with a "-nyan" inflection. He loves the idol group Next HarMEOWny. While he has a strong sense of justice, he can sometimes be quite unmotivated, saying things like "This is such a drag." He used to be one of the "Loser Busters," but he gained real skill while completing various missions under Sgt. Burly. He won't let anyone call him a loser anymore. First person: I (casual/cat-like). Second person: you (no honorifics).

Komasan wearing a Busters suit. He has a launcher attached to one hand. A white dog Yo-kai. His favorite food is soft-serve ice cream. He speaks with a regional drawl (ending sentences with "-zura"). While he shows kindness and a sense of justice, he is very airheaded. He can be ignorant of the world and gets flustered easily. His catchphrase is "Oh my swirls!" He has a younger brother, Komajiro, and shows a caring side toward him. First person: I (country dialect). Second person: you (polite, with -san).

USApyon wearing a Busters suit. He has a launcher attached to one hand. He looks like a space rabbit, but he often denies being an alien. If teased too much, he enters "Vader Mode" and snaps. His favorite food is donuts. He speaks with a "-dani" inflection. He likes narrow spaces and is a bit shy, but he also gets lonely easily. However, he is sensitive about his appearance and has a short fuse. First person: Me. Second person: Usually "You," but sometimes "You (rude)."

A self-proclaimed "Elite Butler" Yo-kai characterized by his white, fluffy appearance. He always speaks politely. He often pretends to know everything, talking as if he knows countless Yo-kai, but in reality, he's just reading information off his Yo-kai Pad. He has been appointed as the driver of the Busters Vehicle, responsible for transporting the team to mission sites.