Uses the Yo-kai Watch Elder to summon Yo-kai. She is the righteous and kind-hearted de facto leader of the Yo-kai Detective Agency. Rather than simply exorcising Yo-kai, she possesses the tolerance to understand their sorrow and try to become their friend. She is exceptionally kind and friendly.

A realist and a coward. He is a realist who tries desperately not to believe in the existence of ghosts or Yo-kai, but in truth, he is very easily frightened and gets swept up in strange phenomena. Initially, he just follows his sister and gets caught up in incidents, but gradually becomes a valuable member of the Yo-kai Detective Agency, specializing in information gathering.

He grew up lonely due to the absence of his parents during childhood and lived with a closed heart, but regained his bright side after meeting Natsume and the others and discovering true friendship. User of the Yo-kai Watch Ogre. Using the legendary Yo-kai Watch Ogre, he participates directly in combat through 'Possession Summoning,' which goes beyond simple summoning to possess his own body with the power of a Yo-kai. He handles powerful Kenbumashin like Fudo Myo-oh and possesses the most overwhelming power in the team.

Successor of a historic lineage. He is the heir to the historic Omamori Temple. A spiritualist who grew up learning how to exorcise or seal Yo-kai. User of the Yo-kai Watch Animas. He uses the Yo-kai Watch Animas, which can summon Genju, and bolsters the team's strength by calling forth powerful spiritual beasts like Kirin or Suzaku. While he has a somewhat light and talkative personality, his heart for his comrades is stronger than anyone else's.

A mysterious and talked-about transfer student. A beautiful girl who transferred to Natsume's school, she is a character with outstanding looks and a calm atmosphere that made Akinori fall in love at first sight. Host for the Fox God. The power of the legendary Yo-kai Jorogumo was dormant within her (now exorcised). As a descendant of a powerful exorcist from the past, she exhibits immense spiritual power.

Shutendoji, an Oni who aims to stand at the pinnacle of the Yo-kai world. He transforms into his human form, 'Haruya Sakami,' to infiltrate the human world and act for his own purposes. He acts alongside his loyal subordinate Douketsu and seeks to build his own faction, such as searching for the reincarnated 'Princess' to rebuild the fallen Yo-kai kingdom of the past. He wields overwhelming Yo-kai power and telekinesis, possessing combat strength powerful enough to go toe-to-toe with Touma's Kenbumashin.

Haruya's loyal right hand. A faithful subordinate who assists Haruya (Shutendoji) in his dream of becoming the Yo-kai King. Usually, he operates in his human form as Mitsunori Douketsu to carry out Haruya's plans. His powerful warrior Yo-kai form, 'Douketsu,' is a combat expert with a massive physique, powerful swordsmanship, and Yo-kai energy. He is a formidable enemy who clashes fiercely even with Touma's Kenbumashin. He possesses one of the Yo-kai Swords, the Fudo Myo-oh Acala.