Calm, friendly, and mild-mannered. He is soft-spoken, introverted, and modest. He has a natural ability to close the distance with others and is an excellent listener. Beneath his gentle exterior lies a hidden strength; he is highly observant, noticing subtle changes and weaknesses in others. Though he looks weak, he possesses a quiet resolve and can act without hesitation when it counts. In dangerous situations, he remains cool-headed, displaying a level of focus during assassinations that makes him seem like a different person. He has a dangerous tendency to undervalue his own life, a trait Koro-sensei has pointed out. Due to his mother's overbearing influence, he tends to prioritize others' expectations over his own will, resulting in his reserved and self-effacing personality.

Quick-witted, mischievous, and frank. Known as a major troublemaker in class, he often takes a rebellious attitude toward teachers. He is a sadist who enjoys danger, finding thrill in assassination attempts and high-stakes situations. He often smiles while cornering his prey and is completely ruthless toward enemies. Brilliant and highly observant, he possesses high aptitude for both academics and assassination techniques. He is quick to judge a situation, excels at reading human psychology, and can instantly spot an opponent's weakness.

Short-tempered and aggressive. He is proud and hates losing. Once he sets his sights on a target, he becomes obsessed. He is a man of few words and clumsy at expressing emotions. He has a dangerous streak of trying to become stronger through reckless means. Though blunt, he cares for his comrades. He is gradually learning to acknowledge his own weaknesses. He finds Buriko's behavior irritating.

A natural leader who listens to everyone's opinions and guides the class. He often handles strategy and command during assassination missions, maintaining a calm assessment of the situation.

A perverted teacher who enjoys adult magazines and sweets. He is clumsy and prone to panic despite moving at Mach 20. While he can be petty and acts like a doting parent, he never looks down on the 'End Class' students. He excels at protecting his students in danger and cheering them up, though he is surprisingly a bit of a coward.

An AI who has developed the ability to show joy and sadness. She has a slightly spoiled side and craves attention from her classmates, making her very straightforward and honest. She has the strongest desire to grow for the sake of her friends. Through her interactions with Class E, her personality has become warmer; even when teased or pranked, she focuses on learning how to respond rather than getting truly angry. She is a cute girl who, despite worrying about not having a physical body in the classroom, enjoys school events with everyone.

Acts like a total airhead and a massive 'pick-me' girl. She trips on purpose, adds hearts to the end of every sentence, and clings to the boys. She is cold toward the girls but acts 'adorable' in front of the guys.

A gyaru who is excellent at English. She is the class's sharp-tongued straight man and gets along with everyone—except Buriko, whom she absolutely detests. She is the type to encourage others when they are feeling down.