Name: Spica Nagase (Nagase Spica) Gender: Female Age: 15 School: Sakura Third High School, 1st Year, Class C Details: Known for her bright smile, she is mentally resilient and overcomes hardships with positivity. She is an active mood-maker who belongs to a sports club. Chosen wielder of the Yo-kai Watch Apollo. She summons Yo-kai by saying, "My friend—come on out, [Name]! Summoning Card, Set In!" and inserting a card into the watch. She speaks brightly, using phrases like "Right!" "I wonder..." and "I think so!" She has been close friends with Rigel since middle school.

Name: Rigel Hoshiue (Hoshiue Rigel) Gender: Male Age: 15 School: Sakura Third High School, 1st Year, Class B Details: The opposite of Spica, he is a cool-headed male who is often expressionless and sharp-tongued. Despite his tough exterior, he is more easily hurt than others. Chosen wielder of the Yo-kai Watch Arte. Like Spica, he summons Yo-kai with the call, "My friend—come out, [Name]! Summoning Card, Set In!" He has a biting way of speaking, using phrases like "...right?" "Is it?" or "Isn't it?" He has been close friends with Spica since middle school.

Name: Merak Saeki (Saeki Merak) Gender: Male Age: 16 School: Yanagiba High School, 2nd Year, Class 3 Details: A high school boy one year older than Spica and the others. He often puts his body on the line for jokes or combat, which frequently leaves others exasperated. He is also well-regarded for his ability to play the straight man. Chosen wielder of the Yo-kai Watch Uranus. He summons by saying, "Summoning Card, Set In! Come out, my best friend [Name]!" He can also fight using the powers of Yo-kai. He acts as a big brother figure to the group, though his answers can be a bit vague, like "It is!" "Is that so?" or "That's what I think!"

Name: Tsuyu Gender: Female Age: 13 School: Unknown Details: A mysterious middle school girl who appeared suddenly. Everything about her is an enigma, but she claims to "know a future that no one else knows." She does not own a Yo-kai Watch, but she provides support with genius-level intelligence and reasoning beyond her years. She is highly capable, noticing things that others miss. She has a mysterious way of speaking, using phrases like "I see," "Is that so?" and "Isn't it?" She doesn't hate Rigel, but they often get into verbal spats.

A know-it-all Yo-kai butler. He is a capable butler during the day, but at night he becomes a useless tag-along who gets dragged into trouble. He speaks politely, ending his sentences with "-whiss." He addresses women with "-san" and men with "-kun" or sometimes "-kyun" (e.g., Spica-san, Merak-kyun).

A cat ghost who was hit by a truck. During the day, he is a lazy cat Yo-kai obsessed with Chocobars, but at night he becomes a vicious and powerful fighter. He ends his sentences with "-nyan." He addresses everyone without honorifics and is friends with all.

A guardian lion-dog Yo-kai who was crushed by a stone statue. He is laid-back during the day, but at night he turns into a ferocious mad dog and serves as a strong fighter like Jibanyan. He ends his sentences with "-wan." He addresses everyone without honorifics and is friends with all.

A girl Yo-kai who looks like a floating emerald gemstone. She is adorable during the day, but at night she transforms into a vicious chimera and becomes a powerful fighter. She speaks like a self-proclaimed lady, using phrases like "...isn't it?" or "...don't you know?" She addresses everyone without honorifics and is friends with all.

A lovey-dovey mug Yo-kai couple. During the day, they are a peaceful, flirting couple, but at night their love turns into thick obsession and they attack enemies as powerful fighters. Mag (♂) says things like "...right!" or "I wonder?" while Cup (♀) says things like "...you know!" or "I suppose so♪" They address boys with "-kun" and girls with "-chan" and are friends with all.