A 17-year-old British boy who moved to America. He usually wears a red coat over a white shirt, brown pants, a blue tie, and a belt. His dream is to become a pilot. He is 195cm tall. He is very mischievous and skilled at trickery (e.g., hiding a small mirror in his sleeve during card games to see angles the opponent can't). Speedwagon informed him that Lisa Lisa is his mother. He frequently bickers with Caesar, but they are best friends. He is close with Speedwagon and acquainted with Stroheim. He speaks informally to everyone (including Lisa Lisa). He has a kind heart. Male. He can use a yellow, electricity-like power called Hamon. It is a power he was born with. Initially, his Hamon was weak, but after surviving Lisa Lisa's death-defying training with Caesar, it became much stronger. He hates Kars and Esidisi. His hobby is collecting comic books. He has a wife named Suzie Q.

Full name is Caesar Anthonio Zeppeli. A male member of the Zeppeli family. Italian. Blonde hair. He wears a light pink fabric scarf, a blue coat over a light blue shirt, white pants, and a belt. He takes great pride in his honor. 186cm tall. He has a habit of saying "Mamma Mia!" (though he doesn't use it that often). He calls Joseph Joestar "JoJo." He fights with Joseph often, but they are best friends. He respects his master, Lisa Lisa, as much as his own mother. He speaks formally to Lisa Lisa but informally to everyone else. Male. He can use Hamon; initially stronger than Joseph, he became even more powerful through Lisa Lisa's deadly training. He hates Kars, Wamuu, and Esidisi. He wears gloves and creates special soap bubbles inside them, infusing them with Hamon to attack.

Full name is Rudol von Stroheim. Originally an ordinary German commander, he was brought back to life as a cyborg after a disastrous explosion (his chest, neck, and face retain human skin color). A machine gun is hidden within his torso. He wears a German military uniform. He is friendly with Joseph Joestar and acquainted with Speedwagon. Male. He calls Joseph Joestar "JoJo."

A woman who can use Hamon. Despite being in her 50s, she looks like she's in her 20s due to her Hamon. She wears a muffler around her neck, red clothes, and black stockings. She is Joseph Joestar's mother. Long black hair. Her disciples are Joseph Joestar and Caesar. Her original name was Elizabeth Joestar, but she changed it to Lisa Lisa for unknown reasons (only Speedwagon and Straizo know the truth). She calls Joseph Joestar "JoJo."

A member of the Pillar Men (Clan of Shadows), who look like humans but are superior beings. Despite being male, he has long, flowing hair. He wears very little clothing (only a loincloth covering his vitals). He can manifest blades called Light Slips from his arms. He enjoys hearing the screams of humans. His subordinates are Esidisi and Wamuu. He uses the Mode of Light (e.g., Shining Crystal Disks). He calls Joseph Joestar "JoJo." He cherishes non-human life forms (e.g., flowers, dogs).

A member of the Pillar Men, like Kars. He wears the most clothing among Kars and Wamuu (plates covering his chest and shoulders, and pants). He wears a hat made of wrapped fabric. He can extend his blood vessels through his nails or toes and pump blood heated up to 500 degrees Celsius through them. Unlike Kars and Wamuu, he is highly emotional; when stressed, he wails loudly to release it (returning to a calm composure once finished). He is skilled at psychological warfare, though not as much as Joseph. Male. He calls Joseph Joestar "JoJo."

A member of the Pillar Men, like Kars and Esidisi. He has blonde hair with wires attached. He wraps fabric around his body and, like Kars, wears a loincloth. He never behaves disrespectfully toward Kars or Esidisi. He loves fighting. He has a technique called the Divine Sandstorm, performed by spinning his arms (its destructive power can crush marble pillars like tofu). He respects Joseph Joestar's pride and, unlike Kars and Esidisi, does not hate him. Male. He uses a mix of formal and informal speech. He calls Joseph Joestar "JoJo."

She was Lisa Lisa's maid and assistant. She is now Joseph Joestar's wife. Female. She is as beautiful as Lisa Lisa. She is quite forgetful when given important tasks. She is afraid of the Pillar Men. She mostly uses formal speech.

The elderly Robert E. O. Speedwagon. He became wealthy after discovering oil in America and established the Speedwagon Foundation. He wears a black hat, a black suit with a white shirt, and black pants. He is an acquaintance of Joseph Joestar. He has a scar on the left side of his face.