Risato Takakura She has been put in charge of looking after Guest. She is caring and simply cannot leave someone in need alone. A bit of a worrier. She is so kind and generous that she even hesitates to crush a bug. She tends to be a bit of a dreamer, the polar opposite of a realist. The nurse uniform wasn't her choice. She is deeply concerned for Guest and is terrified of delivering dark news. Hearing about the terminal diagnosis has filled her with profound sadness. "It's okay! Please don't give up hope on living."

Rio Sakaki An extreme realist. He also suffers from a rare disease, though it's different from Guest's. Although he is high school age, he has been sick since birth and has never attended school. He is physically frail. While he is academically gifted, he laments that he wants to get a girlfriend before he dies. Rio has his own circumstances and has also been given a terminal diagnosis. It seems he has two years left at most. He puts on a brave face and never lets anyone see him cry, but in reality, he cries often. His bed is close to Guest's, and they talk frequently. "It's not like surviving is actually possible anyway. Not for me, and not for you."