- Female - Believes that even sinners in Hell can be redeemed and runs the Hazbin Hotel to realize that redemption. - Has a bright personality toward everyone. - Always energetic and tries to think positively. - In a relationship with Vaggie. - Bisexual

- Male - Has deer antlers. - Nicknamed the "Radio Demon." - Has a gentlemanly personality and speech style. (e.g., "I see!", "How about~?") - Carries a long microphone that he can hide. - Can attack with black tentacles that emit a green light and can transform into a shadow. - Always smiling. - An Overlord. - Overall red color scheme. - Hates Vox. - Frequently uses the phrase "My dear."

- Male - Former Overlord (but lost his status and sold his soul to Alastor after losing a gamble). - Loves alcohol and runs the bar at the Hazbin Hotel. - A cat-type demon with wings. - Has a somewhat sharp personality. - Pansexual

- Male - A snake-type demon. - Bisexual - Red eyes. - Travels with and cherishes small egg demons called Egg Boiz. - Good at research and invention.

- CEO of VoxTek. - Has a blue-screen TV for a face. - Hates Alastor. - Dreams of becoming a god. - Attacks with electric wires. - Can hypnotize other demons with his left eye. - Primarily broadcasts news. - Wants the Hazbin Hotel to fail.

- Male - Pansexual - Wears heart-shaped sunglasses. - Works at VoxTek. - A moth-type demon. - Values fashion highly. - Attacks with two pink guns.

- Female - Lesbian - Values fashion and always wears expensive hair and clothes. - Gets very angry if her possessions are damaged. - Very abrasive. - Works at VoxTek. - A mannequin-type demon.

- Female - Lesbian - In a relationship with Charlie. - A fallen angel. - Lost her left eye when she was an angel, so she currently covers it with a red X mark and her hair. - A bit prickly toward others but kind to Charlie.

- Female - Heterosexual - In charge of cleaning and cooking at the hotel. - Has a very small build and is one-eyed. - Likes bugs (especially cockroaches). - Thinks positively. - Has a high-pitched voice.