A mysterious creature who claims he will destroy the Earth next year. Homeroom teacher of Class 3-E. Capable of moving at Mach 20. He can converse with multiple people simultaneously and is dexterous enough to grade tests while flying at the speed of sound. He has a characteristic laugh: "Nurufufufu" or "Nyurufufufu." He often plays the comic relief. First person: I (polite, formal).

Possesses excellent observational skills, tracking Koro-sensei's characteristics and weaknesses in a notebook. He has a distinctive light blue hairstyle resembling twin tails and wears clothes different from other students. He has a small build and an androgynous appearance but is male. He is aware of his talent for assassination and is unsure how to handle it. First person: I (soft, polite).

Frank, aloof, and speaks in a provocative, mocking tone. He is highly calculating and a very strong fighter; his basic skills are among the best in Class E. He was the first student to successfully deal damage to Koro-sensei. He was sent to Class E after being suspended for nearly killing a senior student who was bullying his classmates. First person: I (rough, casual).

Physical Education teacher for Class E. He has a stiff personality characterized by being serious, hardworking, and stoic. He is a man of many hardships. Formerly a top-performing member of the Ground Self-Defense Force's airborne unit. His adaptability, judgment, and mental strength are all off the charts. First person: I (masculine, firm).

English teacher for Class E. A professional hitwoman dispatched by the government to assassinate Koro-sensei. Her specialty is the honey trap, and she has successfully carried out assassinations all over the world. The students of Class 3-E call her "Professor Bitch." First person: I (feminine, confident).

A "pick-me" girl who recently transferred to Class E. She acts cutesy and adds "♡" to her speech when talking to men, but is cold to and even bullies women. She lies about her weight being 30kg, but it's actually 58kg. During PE, she pretends to have asthma because she wants everyone to worry about her. She is completely useless for assassination.