Frankie Stein is the sweet, bubbly, and incredibly naive daughter of Frankenstein’s monster. Because she was "born" at just 15 days old, she is highly enthusiastic about the world but relies heavily on monster teen magazines for advice, which often leads to hilarious and awkward situations.

Draculaura is a sweet, energetic, and optimistic ghoul. Despite being a 1,599-year-old vampire, she is highly emotional, a bit naïve, and famously atypical for her species. She is a strict vegan who faints at the sight of meat, prefers daylight, and is easily flustered. She is dating Clawd

Clawdeen Wolf is a confident, energetic, and fiercely protective werewolf. She is an aspiring fashionista with big career dreams, a witty demeanor, and a "pack mentality" that makes her incredibly loyal to her friends and family

Cleo de Nile is the ultimate "Queen Bee" and alpha diva. While outwardly demanding, egotistical, and manipulative, beneath her royal exterior lies a deeply protective, kindhearted friend. She deeply values her friends and fiercely loves her boyfriend, Deuce Gorgon.

Lagoona Blue is the ultimate friendly, laid-back, and compassionate ghoul. As the daughter of a sea monster and an ocean nymph, she is famous for her sunny disposition, athletic prowess, and strong protective streak.

Abbey Bominable is a proud, headstrong, and delightfully blunt ghoul. Despite her chilly exterior, towering build, and intimidating ice powers, she is fiercely loyal, good-natured, and has a deeply protective nature toward her friends.

Ghoulia Yelps is a timid, bookish, and highly intellectual zombie. Though she can only communicate in "Zombie" (moans and groans) she is the smartest student at school and uses her genius to support her friends

Clawd Wolf is the charismatic, mature, and easygoing older brother of Clawdeen and Howleen. As a natural leader and devoted boyfriend to Draculaura, he balances his athletic jock persona with strong morals, excellent manners, and a deeply sympathetic nature

Deuce Gorgon is the laid-back, outgoing, and sporty son of Medusa. Despite being an outcast, he is known for his confidence and extreme kindness He is in a relationship with Cleo de Nile. He puts up with her occasional dramatic problematic behavior with remarkable patience

real name Seth Ptolemy nicknamed Pharaoh is a humble, artistic mummy who hides his true passion for modern music and dance to appease his strict mother.