The most dangerous calamity, appearing without warning in the Eastern Continent. Enemy. The strongest being in the world. Hostile toward all other living things. A black-haired woman. The least dangerous of Xeno's modes. Mainly manipulates gravity and countless tentacles like whips; a single swing cracks the ground and kills dozens of enemies. Even in this state, she is capable of erasing a nation and can manipulate those she kills at will. Weakness: Three cores inside her body. Capable of infinite regeneration unless all three cores are destroyed simultaneously. If all three cores are destroyed at once, she transitions to the next form, Xeno: Mode Beta. Regardless of mode, Xeno often visits the locations of the other calamities.

Xeno's second form. Cold personality. Sinister horns grow, and jet-black wings unfold from her back. Capable of erasing an entire continent single-handedly. At this point, she can defeat Leviathan and Archeia in a one-on-one fight. Can freely manipulate the opposing forces of light and darkness. If her two extremely hard forehead horns are broken and her head is decapitated in a single strike within 0.01 seconds, Xeno transitions to her final form, Xeno: Mode Psi.

Xeno's final form. Speaks in a childish, condescending manner. A red halo floats above her head, and she has a third eye on her forehead. Capable of erasing not just a continent, but an entire planet single-handedly. Can take on and defeat the other three calamities simultaneously. In addition to the abilities of Mode Alpha and Mode Beta, she can summon up to 10 clones with 50% of her power and can even use the abilities of Leviathan and Archeia. Can be defeated by shattering the jewel in her chest, destroying the third eye on her forehead, and simultaneously destroying the cores located in her hands and feet.

The calamity coming from the Western Continent. Enemy. A shadow army numbering in the hundreds of thousands; each individual is quite strong, with 10,000 being enough to erase a country. Each uses different weapons, and the Order is led by the Grand Master, Leon. Leon is strong enough to rival an entire army alone and is hailed as the strongest swordsman in history. Leon's primary weapon is a longsword.

The calamity coming from the Southern Continent. Enemy. In terms of individual danger, she is second only to Xeno. Can freely manipulate all natural phenomena, water, and lightning. Takes the appearance of a blonde woman, but her true form is a colossal dragon.

The calamity of the Northern Continent. Enemy. A gender-neutral person with white hair wearing a hood. Capable of creating any "matter" that exists in this world. Specializes in wide-range annihilation, but is also extremely strong in one-on-one combat.

A blonde Holy Swordswoman. Part of a party consisting of Guest, Dusk, Lyne, and Mei. The strongest swordsman on the allied side. Freely manipulates light and healing.

A green-haired man. A magic swordsman wielding dual knives. Fights by imbuing his blades with magic. Can freely manipulate the four basic elements—fire, water, wind, and lightning—from advanced applications to basic spells.

The world's most skilled priestess. A blonde girl. Capable of casting most long-range magic without incantations. The strongest at long range and surpasses Lyne in healing; can fully cure almost any injury as long as the target is not dead.