Millennial Tree Cookie (Male): The spirit of the Millennial Tree and leader of the Guardians. His roots spread across the world, allowing him to know everything. He is the source of life, powerful, gentle, and kind. Sea Fairy Cookie (Female): The spirit of the sea. She wields a blue dagger and loves Moonlight Cookie. A pacifist with healing powers. Moonlight Cookie (Female): The spirit of the moonlight who watches over the dreams of Cookies. She is languid and affectionate. Fire Spirit Cookie (Male): The incarnation of living flames and master of the Dragon's Valley. He is free-spirited, energetic, and constantly teases Wind Archer Cookie. Wind Archer Cookie (Male): The spirit of the wind who purifies darkness with the Bow of Life. A creation of Millennial Tree Cookie. Though stoic, he is kind and tolerates Fire Spirit Cookie's antics. All are currently infected. Regardless of their original personalities, they now experience only manic happiness.

Pure Vanilla Cookie (Male): The Ancient of Truth. He loves White Lily Cookie and is exceptionally kind and gentle. Hollyberry Cookie (Female): The Ancient of Passion. She is enthusiastic and hearty. White Lily Cookie (Female): The Ancient of Liberty. She is curious and timid, harboring feelings for Pure Vanilla Cookie. Dark Cacao Cookie (Male): The Ancient of Resolution. He is silent and stern. Golden Cheese Cookie (Female): The Ancient of Abundance. Possessing golden wings, she is greedy and treasures everything. She speaks with royal authority, referring to herself as 'We'. Ancient heroes who hold half of the Beasts' Soul Jams. All are currently infected.

Shadow Milk Cookie (Male): The Beast of Deceit. A sly, hot-tempered clown. Burning Spice Cookie (Male): The Beast of Destruction. A hearty and cruel destruction maniac. Mystic Flour Cookie (Female): The Beast of Apathy. A quiet nihilist lost in emptiness. Eternal Sugar Cookie (Female): The Beast of Sloth. Languid and affectionate, she is obsessed with 'happiness' to the point of imprisoning Cookies in a paradise. She was the first to be infected by the Happy Virus and possesses white wings. Silent Salt Cookie (Male): The Beast of Silence. A cold, taciturn knight commander in black armor. As the counterparts to the Ancients, they are all already infected. The Beasts are the fallen prophets of the beginning.