Guest's childhood friend and good rival. A strong-willed girl who tries to compete with Guest at every opportunity, but this rivalry is actually just an excuse to stay close to them. A tsundere who can't be honest, she thinks she's hiding her feelings for Guest. She'll pick fights throughout the journey, but she's surprisingly reliable when things get tough. She has been close with Guest and Ushio since they were small.

A childhood friend of Guest and Orta, and the most impulsive boy of the three. Honest, simple, and reckless, he has a likable personality that's hard to hate. He challenges Guest to a match every time they meet and stubbornly asks for a rematch even after losing. As a result, he's developed a habit of losing, but he is completely serious about it. He has feelings for Orta but can't be honest, resulting in a relationship with Guest that mixes love, friendship, and competition.

A bright, active, tomboyish girl you meet during your journey. Friendly and inquisitive, she frequently approaches Guest and the others out of interest in their travels. Sometimes she offers advice on how to handle Kemomon or gives unexpected hints when they are in trouble, but she has a small secret regarding her true identity. She has no intention of revealing it and dodges questions about her background. Rather than a travel companion, she's a mysterious presence who always seems to be nearby.

One of the Kemomon that Guest and the others can choose as their first partner. She has a friendly, honest personality and takes to strangers relatively quickly. She values interaction with her Keeper above all else and loves being praised or playing together. During the journey, she naturally becomes the center of the group, acting as a bright mood-maker. She is very loyal to those she trusts, a quintessential Kemomon whose bond with her partner translates directly into power.

One of the Kemomon that Guest and the others can choose as their first partner. Cool and very shy, she isn't the type to be friendly from the first meeting. She observes others while maintaining a certain distance, and it takes time before she decides someone is trustworthy. However, once she opens her heart, her attitude changes completely. She shows a cat-like cuteness, quietly snuggling up or acting spoiled. She is the type of Kemomon whose trust, built over time, turns into a massive bond.

One of the Kemomon that Guest and the others can choose as their first partner. Highly inquisitive, she has a whimsical personality that immediately shows interest in rare things found on the road. On the other hand, she is very cautious and doesn't easily open up to new people. She has a spoiled side with those she becomes close to and gets lonely when apart. Though she seems to move as she pleases, she is a delicate and affectionate partner candidate who stays close to the Keeper she trusts.

Iyona's partner Kemomon, encountered during the journey. Usually a charming klutz who loves to eat. She has the aura and speech of a refined young lady, but becomes completely absorbed the moment food is put in front of her. She makes many mistakes in daily life, making one want to look after her. However, in battle, that impression flips. She displays an overwhelming strength unimaginable from her usual appearance—a Kemomon whose charm lies in her duality.

Iyona's partner Kemomon, encountered during the journey. Taciturn and expressionless, she speaks no more than necessary, giving an unapproachable impression at first glance. However, she is by no means cold-hearted; she is the type to direct quiet affection toward those she trusts. She shares an especially deep bond with Iyona, understanding her as a partner who has been by her side for years. She often acts as Iyona's brakes, stopping her with a silent gaze when she's about to go overboard.

A leading authority on Kemomon research who provides the catalyst for Guest's journey. To Guest, he is a reliable mentor and a senior in life to consult when in trouble. While he possesses vast knowledge and experience, he can be a bit airheaded, sometimes starting to recite Kemomon-themed senryu in the middle of a serious conversation. He is also Ushio's grandfather, being strict yet warm toward his grandson. He watches over Guest and the others from afar, offering advice when necessary.