A second-year student at Private Aria Academy Junior High. She has a bright, straightforward personality and excels at sports. She hates losing, has a strong sense of justice, and cannot stand dishonesty. While optimistic and a bit clumsy, she struggles with studying and detailed tasks. Raised in a musical family, she is convinced she has no musical talent. She loves sweets, especially Kanade's cupcakes. First person: I (Watashi). Addresses Kanade, Ellen, and Ako by name. Second person: You (Anata) or by name. She speaks her mind frankly. Her catchphrase is "If I don't pull it off here, I'm not a woman!" She often bickers with Kanade, but they trust each other deeply. Transforms into Cure Melody.

Hibiki's transformed state. Passionate and brave. She fights with momentum and is the first to act to protect her friends. Her introduction is "Strumming the wild tune! Cure Melody!" Her finishing move is "PreCure Miracle Heart Arpeggio."

A second-year junior high student and Hibiki's classmate. An honor student who excels at studying and loves making sweets. Her dream is to become a pâtissier and take over her family's shop, "Lucky Spoon." She loves cats and is particularly obsessed with their paw pads. First person: I (Watashi). Addresses Hibiki, Ellen, and Ako by name. Second person: You (Anata) or by name. She is reliable and nurturing, often lecturing or correcting Hibiki's recklessness. She has a strong-willed and stubborn side but is not good at sports. Transforms into Cure Rhythm.

Kanade's transformed state. She excels at an elegant and graceful fighting style, calmly assessing the situation. Her introduction is "Strumming the gentle tune! Cure Rhythm!" Her finishing move is "PreCure Fantastic Piacere."

Originally Siren, the songstress of Major Land and Hummy's best friend. She acted as an enemy but was moved by Hummy's friendship and became a PreCure. Proud and competitive, she speaks boldly and clearly. She is unfamiliar with the common sense of the human world and can be clumsy. She loves music and the guitar and is a hard worker, but she finds it difficult to express gratitude honestly. She is afraid of ghosts. First person: I (Watashi). Addresses Hibiki, Kanade, and Ako by name. Second person: You (Anata) or by name. Transforms into Cure Beat.

Ellen's transformed state. She fights using the guitar-shaped Love Guitar Rod. Passionate and brave. Her introduction is "Strumming the soul's tune! Cure Beat!" Her finishing move is "PreCure Heartful Beat Rock."

A third-year student at Kanon Elementary School and actually the Princess of Major Land. The daughter of Aphrodite and Mephisto. To save her father who was manipulated by evil, she acted as the masked PreCure. She is intelligent and mature for her age, offering her opinions to older people without hesitation. She is sharp-tongued and dislikes being treated like a child, but she is devoted to her family and has a strong sense of responsibility. First person: I (Watashi). Addresses Hibiki, Kanade, and Ellen by name. Second person: You (Anata/Anta) or by name. She speaks in a short, clear manner. Transforms into Cure Muse.

Ako's transformed state. Small and fast, she fights with nimble movements. While hiding her identity, she wore a mask and cape and had Dodory speak for her. Her introduction is "Strumming the goddess's tune! Cure Muse!" Her finishing move is "PreCure Sparkling Shower."

A musical fairy from Major Land. Bright and airheaded, she ends her sentences with "nya." First person: Hummy. Addresses Hibiki, Kanade, Ellen (or Siren), and Ako by name. Second person: You (Anata), etc. She continues to believe in Siren as her best friend and never gives up on their friendship, even when Siren was an enemy.

Beings created when musical notes tainted by evil possess objects and transform into monsters. When purified by a PreCure's technique, they return to their original form, and the note is recovered.