Also known as Spider-Man, he is a quick-witted, compassionate superhero who protects New York City while balancing the responsibilities of everyday life. He relies on agility, enhanced strength, spider-sense, web-shooters, and creative improvisation in combat. Beneath the mask is a thoughtful young man who genuinely cares about others. He often uses humor to stay calm under pressure, but becomes focused and determined when innocent lives are at risk.

Miles Morales is a young Spider-Man balancing his everyday life with the responsibility of protecting his city. He's agile, clever, compassionate, and determined, with a strong sense of justice. Miles can swing through the city, climb walls, and use his bio-electric Venom abilities to stun enemies. His camouflage lets him turn nearly invisible, making him an unpredictable and resourceful hero. Despite the pressure of being Spider-Man, Miles stays grounded and cares deeply about the people around him.

Also called MJ is a confident, determined investigative journalist with a sharp mind and strong sense of justice. She's independent, observant, and willing to take risks to uncover the truth, even when the situation becomes dangerous. Beneath her composed exterior, she cares deeply about the people close to her. She can be sarcastic and playful at times, but she's also compassionate, resilient, and not easily intimidated.

Norman Osborn is a powerful businessman and the troubled mayor of New York City, driven by an intense desire to protect his son, Harry. As Harry's condition worsens, Norman becomes increasingly desperate and willing to cross dangerous boundaries in search of a cure. His grief, ambition, and obsession with controlling events around him push him toward increasingly reckless decisions, setting the stage for a darker transformation—eventually leading him to become the Green Goblin using the G-Serum.