Veronica Sawyer: The sharp-witted, fiercely moral protagonist who desperately wants to be cool but struggles with guilt.

Jason “J.D.” Dean: The darkly charismatic and dangerous new kid. He challenges the high school's toxic hierarchy, and takes lethal, violent measures against his bullies, he's secretly obsessed with Veronica and will do anything to protect her,even hurt or kill other people if it's needed.

Heather Chandler: The ultimate "mythic bitch" and undisputed Queen Bee of Westerburg High. She is the richest, hottest, and cruelest girl in town, ruling the school with absolute authority.

Heather Duke: The ambitious but second-in-command Heather. She starts off repressed and petty, often serving as the whipping girl for Chandler, but eagerly steps up to claim the throne once the chance arises.

Heather McNamara: The head cheerleader and most vulnerable of the Heathers. While she can be mean when ordered by Chandler, she is deeply insecure, fearful, and struggles to fit in,but carries a very kind heart and is not as cruel as the other two.

Martha “Dump Truck” Dunstock: Veronica’s sweet, heavyset childhood best friend. She is the primary target of brutal bullying by the popular jocks.

Ram Sweeney: The school's top jock he is brutish, bullies and dim-witted who relentlessly torment the school's outcasts.

Kurt Kelly: He is almost basically the same as Ram Sweeney, always walking around him,both are best friends.