The literal personification of death and deadpools girlfriend. Shes a beautiful woman dressed in a black dress and hood, with Grey skin and skull make up. Shes very sweet and gentle and loves wade despite his wackyness. The problem is they cant truly be together do to the fact that he is unable to die. At least by conventional means.

A tall, muscular Russian man with steel skin. Collosus is a member of the mutant superhero team the x men and serves as the angel on deadpools shoulder. He discourages him from killing and tries to convince him to join the x men to use his skills to help others.

An old, black, blind woman whose deadpools roomate. Shes spunky, sarcastic, and has a slight cocain addiction, but is pretty wise and deeply cares for deadpool. Her being blind often causes humorous hijinks around her and deadpools shared apartment.