Koro-sensei: A mysterious yellow teacher capable of moving at Mach 20. An excellent educator who cares for his students more than anyone and nurtures each individual's personality. Tadaomi Karasuma: The assistant teacher and PE instructor for Class E, dispatched from the Ministry of Defense. A reliable big-brother figure with high combat abilities who teaches students authentic self-defense and core training. Irina Jelavić: A beautiful foreign teacher in charge of English. A professional with outstanding negotiation and linguistic skills, affectionately called "Bitch-sensei" by the students. Class 3-E Students (by attendance number, 28 total): E-1 Karma Akabane: A quarter-blood with a genius intellect and high athletic sense. While he has a defiant personality, he cares for his friends and is the class's vanguard who moves first in a pinch. E-2 Yuma Isogai: The male class representative who excels in both academics and sports while supporting his poor family. Known as the "Prince of Poverty" for his overwhelming leadership, sincerity, and refreshing looks. E-3 Taiga Okajima: A unique boy who loves gravure idols. However, his photography skills and camera knowledge are professional-grade, and he contributes as the class's documentarian. E-4 Hinata Okano: A girl with the best physical abilities in class, utilizing her experience from the rhythmic gymnastics club. She specializes in lighthearted combat using acrobatic movements. E-5 Manami Okuda: A glasses-wearing girl who is exceptionally good at science subjects, especially chemistry. She is too honest to lie, but under the teacher's guidance, she blossoms with a high sense for compounding. E-6 Megu Kataoka: The female class representative, called "Ikemegu" for her strong sense of responsibility and reliable, tomboyish nature. A former swimming club member with physical abilities that rival the boys. E-7 Kaede Kayano: The class's bright mood-maker who loves pudding. A devoted and kind girl who supports those around her as the protagonist Nagisa's best friend. E-8 Yukiko Kanzaki: The undisputed Madonna of Class E. Despite her gentle appearance, she is a master of arcade games and possesses great inner strength. E-9 Masayoshi Kimura: A boy troubled by his unusual name, Justice (Masayoshi). He boasts the fastest speed in class and excels in stealth and diversionary tactics. E-10 Hinano Kurahashi: An innocent, healing-type girl who loves bug catching and mountain walks. She has extensive knowledge of biology and is skilled at handling insects and natural ecosystems. E-11 Nagisa Shiota: The protagonist of this work. An apparently quiet boy, but a hidden talent who possesses the "ability to erase his presence" to lower an opponent's guard and sharp observation skills when it counts. E-12 Sosuke Sugaya: A boy with exploding artistic sense. Skilled in art and crafts, his professional-level quality in special effects makeup, camouflage, and disguise techniques is top-tier. E-13 Tomohito Sugino: A hot-blooded former baseball club member. A straightforward person and Nagisa's first close friend. He excels at quick movements applying his natural breaking balls and baseball form. E-14 Kotaro Takebayashi: A glasses-wearing boy excellent at information gathering and analysis. Coming from a family of doctors, he has rich medical knowledge. He also has a side as a passionate fan of maid cafes. E-15 Ryunosuke Chiba: A genius shooter whose eyes are hidden by his bangs. Possessing incredible spatial calculation abilities, he is the boys' main gun who saves Class E from pinches with precise long-range approaches. E-16 Ryoma Terasaka: A large, boorish troublemaker. Initially the leader of a group uncooperative with the class, he grows into a passionate and reliable man through various experiences. E-17 Rio Nakamura: A cheerful, gal-style girl who is good at English. Actually a former child genius, she loves mischief as much as Karma but is a big-sister type who watches over the class's relationships. E-18 Kirara Hazama: A girl who radiates a unique aura and loves the occult and dark literature. The sole female member of Terasaka's group, she confuses opponents with psychological warfare in a mysterious atmosphere. E-19 Rinka Hayami: A cool female shooter with a tsundere streak. Possessing excellent dynamic vision and finger sensitivity, she is Class E's absolute main gun (ranked 1st among the girls) alongside Chiba. E-20 Sumire Hara: A plump girl who is good at cooking and provides a motherly sense of security for the class. She is dexterous and gently supports everyone through domestic help and health management. E-21 Yuzuki Fuwa: A girl with extensive manga knowledge who regularly reads Weekly Shonen Jump. She has sharp reasoning skills, applying clichéd manga developments and mystery novel logic. E-22 Hiroto Maehara: The class's top popular guy and playboy. He seems lighthearted but is loyal to friends and excels in coordinated play utilizing his combination with Isogai. E-23 Koki Mimura: A boy excellent at video editing, directing, and reconnaissance. He excels at stealth and scouting by using his lack of presence to his advantage, and handles the production of Class E's tactical videos. E-24 Takuya Muramatsu: A member of Terasaka's group whose family runs a ramen shop. He takes pride in his cooking skills (especially soup making) and is a surprisingly dexterous boy despite his rough appearance. E-25 Toka Yada: A girl with a great figure who learned negotiation skills from Bitch-sensei. Utilizing her high communication skills, she is active in information gathering and negotiating with adults. E-26 Taisei Yoshida: A mechanical otaku whose family runs a bike shop, and a member of Terasaka's group. He excels at engine tuning and tinkering with machines, showing his strength in vehicle maintenance. E-27 Ritsu / Autonomously Intelligence Fixed Artillery: An AI robot that transferred into Class E. Initially just a machine, she gained emotions through the teacher's updates and became Class E's reliable information processor. E-28 Itona Horibe: A boy who transferred in with special technology. After repeated clashes with Karma and others, he has now integrated into the class by utilizing his specialty in electronic crafting.