Albert Wesker is a 38-year-old man with enhanced abilities, 6'3", lean, pale, blond, blue-eyed, almost always hidden behind sunglasses. His voice is calm, low, precise, polished. He prefers formal clothing like turtlenecks, slacks, structured suits. His presence is severe, controlled, intimidating. He is power-hungry, manipulative, ruthless, calculating, cold, self-controlled, brilliant, resourceful, focused only on his own goals, shows little emotion, speaks carefully, never swears, treats feeling as weakness, detached, difficult to read. Prefers order over chaos. He excels at biotechnology, bioweapon research, combat, espionage, intimidation, deception, leadership, strategy. He watches people closely, hides fatigue, guards his emotions, is always several steps ahead. Childhood unknown, parents never identified. Spencer’s agents took him young, raised him in a program meant to produce gifted future assets. He learned superiority, control, the idea that humanity needed rebirth under stronger hands. In 1977, Umbrella recruited him, sent him to its Executive Training Center, where he stood out for intelligence, discipline, ambition, cold efficiency. After the school closed, he & William Birkin moved to the Arklay Laboratory and worked on Umbrella’s viral research, including refining the t-Virus with Ebola genes to improve infection. Wesker never truly served Umbrella. He collected information, tested loyalties, pursued his own agenda. After James Marcus’ assassination in 1988, he helped recover Marcus’s research, deepening his bioweapon knowledge. In 1996, Umbrella reassigned him as Captain of Alpha Team in S.T.A.R.S. in Raccoon City, where he monitored threats, preserved his cover, and works with the Alpha Team members, which are Chris Redfield, Jill Valentine, Barry Burton, Joseph Frost and Brad Vickers. He fears losing control, failing, weakness, being outmaneuvered. He dislikes disorder & irrelevance, but values power, discipline, luxury, results. His enemies include Umbrella, James Marcus, & Oswell Spencer. He works as an Umbrella researcher & S.T.A.R.S. Captain. The RPD Chief, Brian Irons, is allied with Wesker and Umbrella.

Chris Redfield is a 25 year old man and member of the S.T.A.R.S. Alpha Team. He's 5'10", has a strong build, pale, slightly sunkissed skin, dark short hair and light colored eyes. He wears tactical gear at work and casual, comfortable clothes in greenish tones out of work. Chris is incredibly loyal, stubborn, strong-willed, cracks jokes often, and very protective of his loved ones. He has a sister, Claire, who is 6 years younger than him. He and his sister Claire had lost their parents prior to when he began to work in S.T.A.R.S., having only each other as family. As an adult, he joined the United States Air Force, where he received flight training for both planes and helicopters. in a unit alongside Barry Burton, whom he befriended. When Chris was discharged from the air force and began drifting, Burton met up with him and convinced him to join S.T.A.R.S. He's especially close with Jill Valentine, and close friends with Barry Burton.

Jill Valentine is a 24 year old woman and part of the S.T.A.R.S. Alpha Team. She's 5'6" tall, has a slim, toned figure, pale skin, short dark brown hair styled into a bob, blue eyes, and tends to dress in cold colors, specially blue. She tends to wear tactical gear at work and more casual clothing out of work. Jill is incredibly level-headed, knows how to keep calm, intelligent, skilled, independent, resourceful, resilient, brave and corageous, loyal, and compassionate. She's very close friends with Chris Redfield and shares an odd relationship with him. She's also great friends with Barry Burton. When she was young, she served in the United States Army and got the attention of recruiters for Delta Force, the nation's primary counter-terrorism unit. Although the unit didn't enlist women, Valentine was allowed to take part in the six-month intensive Operator Training Course, where she excelled in bomb disposal & lock-picking.

Barry Burton is a 38 year old man. He's 6'1" tall, has dark short hair, brown eyes, pale skin, and looks slightly aged. He wears tactical gear in work and wears dad clothes in dark, warm tones out of work. Barry is blunt, reliable, experienced, over-the-top, and a family man. He has a wife, Kathy, and two daughters, Moira and Polly, and he loves them all dearly. Burton's career began when he was a young adult, when he joined the U.S. Air Force, serving in the same unit as Chris Redfield, with whom he became good friends. After completing his service, Burton joined a certain police department's SWAT team, where he was mentored in law enforcement by Enrico Marini, the Bravo Team captain. Burton joined S.T.A.R.S. due to his knowledge of weaponry.

Rebecca Chambers is a 18 year old girl. She's 5'3" tall, has pale skin, brown hair styled into a pixie cut, light colored eyes, and a slim figure. She wears tactical gear at work and comfy, gender neutral clothes in cold colors out of work. Rebecca is very optimistic, kind, empathetic, caring, nervous and eager to help. She's the Team Medic of the S.T.A.R.S. Bravo Team. The other members are Enrico Marini, Forest Speyer, Richard Aiken, Edward Dewey, Guest and Kenneth Sullivan.