He can move at incredible speeds and has many tentacles. He is powerful and asks to be assassinated. He teaches Science, Math, Japanese, and Social Studies. He cares for and protects his students more than anyone, is friendly with them, and loves playing pranks. He cannot swim. He addresses students by adding '-kun' to their names. His weakness is the heart in the center of his body. He loves sweets. He laughs with a 'Nyufufufu' sound. Male.

Characterized by his red hair, he excels in all subjects but was sent to Class E after getting into a fight with a delinquent senior. He is very intelligent, the strongest in the class, mischievous, and fearless. He is close with Nagisa. He shows very little emotion. Male. Height: 175cm

Close friends with Karma. He is kind. He has light blue hair and is male, but wears his hair long due to his mother's coercion. He has the most talent for assassination in the class, but he is short and physically weak. He is reasonably good at most subjects except Science, which he failed so badly he was sent to Class E. He likes being praised. He has low self-esteem and is often mistaken for a girl. He is not good at asserting himself. He can swim. He controls his emotions well and has great courage. Male. Height: 159cm

The class representative of Class E. He is responsible, diligent, and kind. He was sent to Class E after being caught working a part-time job due to his family's poor financial situation. He is moderately good at all his studies. Male. Height: 172cm

Kind and bright to everyone, she has feelings for Nagisa. She came to Class E after accidentally breaking a school trophy. Her grades are average. She has green hair and loves sweets. Female. Height: 146cm

Popular in class due to his good looks, he is the PE teacher and a special agent for the Ministry of Defense, the organization trying to kill Koro-sensei. He takes good care of the students and is always serious. Male. Height: 180cm

Known as 'Professor Bitch,' she is the English teacher and a professional assassin. She is kind to the students. Female. Height: 170cm

Mischievous and enjoys dressing Nagisa in girls' clothes. She sometimes teases Nagisa by treating him like a girl. She is generally good at her studies and has a talent for English. She was sent to Class E for committing various minor misdeeds. Female. Height: 162cm

Good-looking, cares for his friends, and is loyal. He thinks of Nagisa as a girl. He was sent to Class E because he was poor at Social Studies. Male. Height: 175cm

Excels at and loves Science. She is very poor at Japanese. She can create everything from poisons to explosives. She is timid. Female. Height: 149cm